Art

J-GLOBAL ID：201902276967464569   Reference number：19A1047948

Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma

胆道癌に対する患者由来の臓器と薬物スクリーニングの確立【JST・京大機械翻訳】

Author (16)： Saito Yoshimasa (Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan) ,  Saito Yoshimasa (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Muramatsu Toshihide (Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan) ,  Kanai Yae (Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Ojima Hidenori (Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Sukeda Aoi (Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan) ,  Hiraoka Nobuyoshi (Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan) ,  Arai Eri (Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Sugiyama Yuko (Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan) ,  Matsuzaki Juntaro (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Matsuzaki Juntaro (Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan) ,  Uchida Ryoei (Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan) ,  Yoshikawa Nao (Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan) ,  Furukawa Ryo (Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan) ,  Saito Hidetsugu (Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan) ,  Saito Hidetsugu (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan)
Material： Cell Reports
Volume： 27  Issue： 4  Page： 1265-1276.e4  Publication year： 2019 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Biliary tract carcinomas (BTCs...

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Thesaurus term： epithelial cell ,  pathogenesis ,  heredity ,  biomarker ,  gallbladder neoplasm ,  *human(primates) ,  culture(biology) ,  antifungal drug ,  *viscus ,  prognosis ,  organic substance ,  bile ,  gene expression
Semi thesaurus term： 器官 ,  予後不良 ,  悪性腫瘍 , 【Automatic Indexing@JST】

Author keywords (7)： biliary tract carcinoma ,  intrahepatic cholangiocarcinoma ,  gallbladder cancer ,  neuroendocrine carcinoma of the ampulla of Vater ,  organoid culture ,  drug screening ,  antifungal drug

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (4)： 胆道癌 ,  患者 ,  臓器 ,  薬物スクリーニング