Art

J-GLOBAL ID：201902278903503205   Reference number：19A1308630

Establishment of a Mouse Model of Atopic Dermatitis by Deleting Ikk2 in Dermal Fibroblasts

皮膚線維芽細胞におけるIKK2欠失によるアトピー性皮膚炎のマウスモデルの確立【JST・京大機械翻訳】

Author (15)： Nunomura Satoshi (Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan) ,  Ejiri Naoko (Department of Clinical Laboratory and Molecular Pathology, Graduate School of Medical and Pharmaceutical Science, University of Toyama, Toyama, Japan) ,  Kitajima Midori (Department of Clinical Laboratory and Molecular Pathology, Graduate School of Medical and Pharmaceutical Science, University of Toyama, Toyama, Japan) ,  Nanri Yasuhiro (Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan) ,  Arima Kazuhiko (Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan) ,  Mitamura Yasutaka (Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan) ,  Yoshihara Tomohito (Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan) ,  Fujii Kazuki (Life Science Research Center, University of Toyama, Toyama, Japan) ,  Fujii Kazuki (Department of Behavioral Physiology, Graduate School of Innovative Life Science, University of Toyama, Toyama, Japan) ,  Takao Keizo (Life Science Research Center, University of Toyama, Toyama, Japan) ,  Takao Keizo (Department of Behavioral Physiology, Graduate School of Innovative Life Science, University of Toyama, Toyama, Japan) ,  Imura Johji (Department of Diagnostic Pathology, Graduate School of Innovative Life Science, University of Toyama, Toyama, Japan) ,  Fehling Hans Joerg (Institute of Immunology, University Hospital of Ulm, Ulm, Germany) ,  Izuhara Kenji (Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan) ,  Kitajima Isao (Department of Clinical Laboratory and Molecular Pathology, Graduate School of Medical and Pharmaceutical Science, University of Toyama, Toyama, Japan)
Material： Journal of Investigative Dermatology  (J Invest Dermatol)
Volume： 139  Issue： 6  Page： 1274-1283  Publication year： 2019 
JST Material Number： H0776A  ISSN： 0022-202X  CODEN： JIDEAE  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Atopic dermatitis is a chronic...

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Thesaurus term： human ,  Phenotype ,  immunosuppression ,  keratinocyte ,  Inflammation ,  *fibroblast ,  pathogenesis ,  complex (substance) ,  Pruritus ,  *atopic dermatitis ,  paradox ,  *Dermatitis ,  molecular mechanism ,  *mouse model ,  *skin fibroblast ,  reaction ,  immune response ,  suppression and control
Semi thesaurus term： 慢性化 , 【Automatic Indexing@JST】

JST classification (3)： Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Skin diseases  (GF03000Q) ,  Basic dermatology  (GF01020Y)

Terms in the title (5)： 皮膚線維芽細胞 ,  IKK2 ,  欠失 ,  アトピー性皮膚炎 ,  マウスモデル