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J-GLOBAL ID：201902280995156834   Reference number：19A1873523

SKO1 deficiency extends chronological lifespan in Saccharomyces cerevisiae

Saccharomyces cerevisiaeにおけるSKO1遺伝子欠損は経時的寿命を延長する

Author (8)： MASUMURA Koji (Hiroshima Univ., Higashi-Hiroshima, JPN) ,  MATSUKAMI Sachi (Hiroshima Univ., Higashi-Hiroshima, JPN) ,  YONEKITA Kumiko (Hiroshima Univ., Higashi-Hiroshima, JPN) ,  KANAI Muneyoshi (National Res. Inst. of Brewing, Higashi-Hiroshima, JPN) ,  KUME Kazunori (Hiroshima Univ., Higashi-Hiroshima, JPN) ,  HIRATA Dai (Hiroshima Univ., Higashi-Hiroshima, JPN) ,  HIRATA Dai (Asahi Sake Brewing Co. Ltd., Nagaoka, JPN) ,  MIZUNUMA Masaki (Hiroshima Univ., Higashi-Hiroshima, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 83  Issue： 8  Page： 1473-1476  Publication year： Aug. 2019 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *Saccharomyces cerevisiae ,...
Semi thesaurus term： hog1遺伝子 ,...

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JST classification (3)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S) ,  Microorganism biochemistry  (EG03020N)

Reference (12)：

• Rep M, Proft M, Remize F, et al. The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage. Mol Microbiol. 2001;40:1067-1083.
• Proft M, Struhl K. Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Mol Cell. 2002;9:1307-1317.
• Saito H, Posas F. Response to hyperosmotic stress. Genetics. 2012;192:289-318.
• Kobayashi Y, Inai T, Mizunuma M, et al. Identification of Tup1 and Cyc8 mutations defective in the responses to osmotic stress. Biochem Biophys Res Commun. 2008;368:50-55.
• Fontana L, Partridge L, Longo VD. Extending healthy life span-from yeast to humans. Science. 2010;328:321-326.

Terms in the title (4)： Saccharomyces ,  遺伝子欠損 ,  経時 ,  寿命