Art

J-GLOBAL ID：201902284729916744   Reference number：19A1898191

Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

Acremonium egypiacumにおけるアスコフラノンとアスコクロリンの完全な生合成経路【JST・京大機械翻訳】

Author (26)： Araki Yasuko (Research and Development Division, Kikkoman Corporation, Noda City, Chiba 278-0037, Japan) ,  Awakawa Takayoshi (Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan) ,  Awakawa Takayoshi (Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Tokyo 113-8657, Japan) ,  Matsuzaki Motomichi (Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Matsuzaki Motomichi (School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki City, Nagasaki 852-8523, Japan) ,  Matsuzaki Motomichi (Department of Parasitology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan) ,  Cho Rihe (Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Matsuda Yudai (Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan) ,  Hoshino Shotaro (Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan) ,  Shinohara Yasutomo (Research and Development Division, Kikkoman Corporation, Noda City, Chiba 278-0037, Japan) ,  Yamamoto Masaichi (Institute of Mitochondrial Science Company, Ltd., Tokyo 176-0025, Japan) ,  Kido Yasutoshi (Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Kido Yasutoshi (Institute of Mitochondrial Science Company, Ltd., Tokyo 176-0025, Japan) ,  Kido Yasutoshi (Department of Parasitology, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan) ,  Kido Yasutoshi (Research Center for Infectious Disease Sciences, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan) ,  Inaoka Daniel Ken (Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Inaoka Daniel Ken (School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki City, Nagasaki 852-8523, Japan) ,  Inaoka Daniel Ken (Department of Host-Defense Biochemistry, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan) ,  Nagamune Kisaburo (Department of Parasitology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan) ,  Nagamune Kisaburo (Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan) ,  Ito Kotaro (Research and Development Division, Kikkoman Corporation, Noda City, Chiba 278-0037, Japan) ,  Abe Ikuro (Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan) ,  Abe Ikuro (Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Tokyo 113-8657, Japan) ,  Kita Kiyoshi (Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Kita Kiyoshi (School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki City, Nagasaki 852-8523, Japan) ,  Kita Kiyoshi (Department of Host-Defense Biochemistry, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 116  Issue： 17  Page： 8269-8274  Publication year： 2019 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Ascofuranone (AF) and ascochlo...

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Thesaurus term： in vitro experiment ,  biological activity ,  antitumor action ,  *biosynthesis ,  cluster ,  transcription factor ,  secondary metabolite ,  gene ,  Heredity ,  reconstitution ,  heterologous expression ,  *Biosynthetic Pathways ,  *Acremonium ,  ketone ,  aromatic aldehyde ,  diene ,  oxygen heterocyclic compound ,  aromatic chlorine compound ,  polyphenol
Semi thesaurus term： *Acremonium , 【Automatic Indexing@JST】

Author keywords (5)： ascofuranone ,  ascochlorin ,  secondary metabolism ,  terpene cyclase ,  African trypanosomiasis

JST classification (1)： Structure and chemistry of genes  (EC02020U)

Substance index (2)： Ascochlorin ,  Ascofranone

Terms in the title (4)： Acremonium ,  アスコフラノン ,  アスコクロリン ,  生合成経路