Art

J-GLOBAL ID：201902285379676612   Reference number：19A0743405

FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration

FoxO3改変ヒトESC由来血管細胞は血管保護と再生を促進する【JST・京大機械翻訳】

Author (36)： Yan Pengze (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China) ,  Yan Pengze (State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China) ,  Yan Pengze (University of the Chinese Academy of Sciences, Beijing 100049, China) ,  Li Qingqing (Beijing Advanced Innovation Center for Genomics and Biomedical Pioneering Innovation Center, College of Life Sciences, Peking University, Beijing 100871, China) ,  Wang Lixia (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China) ,  Wang Lixia (University of the Chinese Academy of Sciences, Beijing 100049, China) ,  Lu Ping (Beijing Advanced Innovation Center for Genomics and Biomedical Pioneering Innovation Center, College of Life Sciences, Peking University, Beijing 100871, China) ,  Suzuki Keiichiro (Institute for Advanced Co-Creation Studies, Graduate School of Engineering Science, Osaka University, Osaka 560-8531, Japan) ,  Suzuki Keiichiro (Graduate School of Engineering Science, Osaka University, Osaka 560-8531, Japan) ,  Liu Zunpeng (State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China) ,  Liu Zunpeng (University of the Chinese Academy of Sciences, Beijing 100049, China) ,  Lei Jinghui (Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China) ,  Li Wei (Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China) ,  He Xiaojuan (Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China) ,  Wang Si (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China) ,  Ding Jianjian (Army Diagnosis and Treatment Center for Oral Disease, 306th Hospital of the PLA, Beijing 100101, China) ,  Chan Piu (Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China) ,  Zhang Weiqi (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China) ,  Zhang Weiqi (University of the Chinese Academy of Sciences, Beijing 100049, China) ,  Zhang Weiqi (Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China) ,  Zhang Weiqi (Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China) ,  Song Moshi (University of the Chinese Academy of Sciences, Beijing 100049, China) ,  Song Moshi (State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China) ,  Song Moshi (Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China) ,  Izpisua Belmonte Juan Carlos (Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA) ,  Qu Jing (State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China) ,  Qu Jing (University of the Chinese Academy of Sciences, Beijing 100049, China) ,  Qu Jing (Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China) ,  Tang Fuchou (Beijing Advanced Innovation Center for Genomics and Biomedical Pioneering Innovation Center, College of Life Sciences, Peking University, Beijing 100871, China) ,  Tang Fuchou (Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China) ,  Tang Fuchou (Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing 100871, China) ,  Liu Guang-Hui (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China) ,  Liu Guang-Hui (University of the Chinese Academy of Sciences, Beijing 100049, China) ,  Liu Guang-Hui (Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China) ,  Liu Guang-Hui (Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China) ,  Liu Guang-Hui (Beijing Institute for Brain Disorders, Beijing 100069, China)
Material： Cell Stem Cell
Volume： 24  Issue： 3  Page： 447-461.e8  Publication year： 2019 
JST Material Number： W3106A  ISSN： 1934-5909  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： FOXO3 is an evolutionarily con...

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Thesaurus term： therapy ,  transcription factor ,  safety ,  nucleotide ,  ES cell ,  ischemia ,  wild type ,  *human(primates) ,  *blood vessel ,  senile change ,  tumorigenesis ,  down-regulation ,  in vitro experiment
Semi thesaurus term： マウスモデル ,  *血管細胞 , 【Automatic Indexing@JST】

Author keywords (5)： FOXO3 ,  stem cell ,  gene editing ,  aging ,  vascular cells

JST classification (1)： Gene expression  (EC02040Q)

Terms in the title (6)： FoxO3 ,  改変 ,  ヒト ,  血管細胞 ,  血管 ,  促進