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J-GLOBAL ID：201902285775673437   Reference number：19A1396809

Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis

ZScan5B欠損はDNA損傷応答を損ない,有糸分裂中の染色体異常を引き起こす【JST・京大機械翻訳】

Author (18)： Ogawa Seiji (Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan) ,  Ogawa Seiji (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Yamada Mitsutoshi (Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan) ,  Nakamura Akihiro (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Sugawara Tohru (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Nakamura Akari (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Miyajima Shoko (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Harada Yuichirou (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Ooka Reina (Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan) ,  Okawa Ryuichiro (Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan) ,  Miyauchi Jun (Department of Central Laboratory, Saitama Municipal Hospital, 2460 Midori-ku, Saitama, Saitama-ken 336-8522, Japan) ,  Tsumura Hideki (Division of Laboratory Animal Resources, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Yoshimura Yasunori (Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan) ,  Miyado Kenji (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Akutsu Hidenori (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Tanaka Mamoru (Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan) ,  Umezawa Akihiro (Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, Japan) ,  Hamatani Toshio (Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan)
Material： Stem Cell Reports
Volume： 12  Issue： 6  Page： 1366-1379  Publication year： 2019 
JST Material Number： W3132A  ISSN： 2213-6711  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Zygotic genome activation (ZGA...

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Thesaurus term： chromatin ,  fertilization(reproduction) ,  *mitosis ,  ES cell ,  gene ,  *DNA lesion ,  versatility ,  genome ,  completeness ,  *chromosomal aberration
Semi thesaurus term： 共免疫沈降法 ,  ヒストンH2AX ,  ドメイン構造 ,  ゲノム安定性 ,  *DNA損傷応答 , 【Automatic Indexing@JST】

Author keywords (8)： Zscan5b ,  genome integrity ,  mitosis ,  postreplicative DNA damage repair ,  embryonic stem cell ,  knockout mouse ,  chromosome instability syndrome ,  mosaicism

JST classification (3)： Cell physiology in general  (EF02010S) ,  Development(=generation)and differentiation  (EJ16020W) ,  Gene expression  (EC02040Q)

Terms in the title (4)： 欠損 ,  DNA損傷応答 ,  有糸分裂 ,  染色体異常