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J-GLOBAL ID：201902289283605910   Reference number：19A1171462

Hydrochlorothiazide ameliorates polyuria caused by tolvaptan treatment of polycystic kidney disease in PCK rats

ヒドロクロロチアジドはPCKラットにおいて,多発性嚢胞腎症のトルバプタン治療を原因とする多尿症を改善する

Author (11)： Wang Anyi (Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Hirose Takuo (Division of Nephrology and Endocrinology, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Ohsaki Yusuke (Division of Integrated Renal Replacement Therapy, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Takahashi Chika (Division of Integrated Renal Replacement Therapy, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Sato Emiko (Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Oba-Yabana Ikuko (Division of Nephrology and Endocrinology, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Kinugasa Satoshi (Division of Nephrology and Endocrinology, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Muroya Yoshikazu (Division of Nephrology and Endocrinology, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Ito Sadayoshi (Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Mori Takefumi (Division of Nephrology and Endocrinology, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Mori Takefumi (Division of Integrated Renal Replacement Therapy, Department of Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan)
Material： Clinical and Experimental Nephrology (Web)
Volume： 23  Issue： 4  Page： 455-464  Publication year： 2019 
JST Material Number： U1582A  ISSN： 1342-1751  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *diuretic ,...
Semi thesaurus term： aquaporin ,...

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Author keywords (4)： V2 receptor antagonist ,  Antidiuretics ,  Glomerular filtration rate ,  Diabetes insipidus

JST classification (2)： Basic medicine on urogenital system  (GM01020T) ,  Basic research of drugs acting on urinary system  (GW11010R)

Substance index (2)： OPC-41061 ,  Hydrochlorothiazide

Terms in the title (7)： ヒドロクロロチアジド ,  ラット ,  多発性嚢胞腎 ,  トルバプタン ,  治療 ,  原因 ,  多尿症