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J-GLOBAL ID：201902290358101524   Reference number：19A0418714

Copper diethyldithiocarbamate as an inhibitor of tissue plasminogen activator synthesis in cultured human coronary endothelial cells

培養ヒト冠動脈内皮細胞における組織プラスミノーゲン活性化因子合成の阻害剤としてのジエチルジチオカルバミン酸銅

Author (7)： FUJIE Tomoya (Tokyo Univ. Sci., Noda, JPN) ,  FUJIE Tomoya (Toho Univ., Funabashi, JPN) ,  OKINO Shiori (Tokyo Univ. Sci., Noda, JPN) ,  YOSHIDA Eiko (Tokyo Univ. Sci., Noda, JPN) ,  YAMAMOTO Chika (Tokyo Univ. Sci., Noda, JPN) ,  NAKA Hiroshi (Nagoya Univ., Nagoya, JPN) ,  KAJI Toshiyuki (Tokyo Univ. Sci., Noda, JPN)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 42  Issue： 5  Page： 553-558(J-STAGE)  Publication year： 2017 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： vascular endothelial cell ,...

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JST classification (2)： Basic hematology  (GK01020N) ,  Enzyme in general  (EB09010D)

Substance index (1)： Bis(diethylaminocarbonothioylthio) copper(II)

Reference (16)：

• Francis, R.B.Jr. and Neely, S. (1989): Inhibition of endothelial secretion of tissue-type plasminogen activator and its rapid inhibitor by agents which increase intracellular cyclic AMP. Biochim. Biophys. Acta, 1012, 207-213.
• Fujie, T., Hara, T. and Kaji, T. (2016a): Toxicology of organic-inorganic hybrid molecules: Bio-organometallics and its toxicology. J. Toxicol. Sci., 41, SP81-SP88.
• Fujie, T., Murakami, M., Yoshida, E., Tachinami, T., Shinkai, Y., Fujiwara, Y., Yamamoto, C., Kumagai, Y., Naka, H. and Kaji, T. (2016d): Copper diethyldithiocarbamate as an activator of Nrf2 in cultured vascular endothelial cells. J. Biol. Inorg. Chem., 21, 263-273.
• Fujie, T., Murakami, M., Yoshida, E., Yasuike, S., Kimura, T., Fujiwara, Y., Yamamoto, C. and Kaji, T. (2016c): Transcriptional induction of metallothionein by tris(pentafluorophenyl)stibane in cultured bovine aortic endothelial cells. Int. J. Mol. Sci., 17, 1381.
• Fujie, T., Segawa, Y., Yoshida, E., Kimura, T., Fujiwara, Y., Yamamoto, C., Satoh, M., Naka, H. and Kaji, T. (2016b): Induction of metallothionein isoforms by copper diethyldithiocarbamate in cultured vascular endothelial cells. J. Toxicol. Sci., 41, 225-232.

Terms in the title (8)： 培養 ,  ヒト ,  冠動脈 ,  内皮細胞 ,  組織プラスミノーゲン活性化因子 ,  阻害剤 ,  ジエチルジチオカルバミン酸 ,  銅