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J-GLOBAL ID：201902291671474305   Reference number：19A0963320

Expression, Functional Characterization, and Preliminary Crystallization of the Cochaperone Prefoldin from the Thermophilic Fungus Chaetomium thermophilum

好熱性真菌chaeomium thermophilum由来のコシャペロンであるプレフォルジンの発現,機能特性化及び予備的結晶化【JST・京大機械翻訳】

Author (17)： Morita Kento (Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan) ,  Yamamoto Yohei Y. (Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan) ,  Hori Ayaka (Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan) ,  Obata Tomohiro (Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan) ,  Uno Yuko (Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan) ,  Shinohara Kyosuke (Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan) ,  Noguchi Keiichi (Instrumentation Analysis Center, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan) ,  Noi Kentaro (Department of Molecular Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.) ,  Noi Kentaro (Core Research for Evolutional Science and Technology (CREST), JST, Kawaguchi, Saitama 332-0012, Japan) ,  Ogura Teru (Department of Molecular Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.) ,  Ogura Teru (Core Research for Evolutional Science and Technology (CREST), JST, Kawaguchi, Saitama 332-0012, Japan) ,  Ishii Kentaro (Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Myodaiji, Okazaki 444-8787, Japan) ,  Kato Koichi (Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Myodaiji, Okazaki 444-8787, Japan) ,  Kikumoto Mahito (Structural Biology Research Center, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya, Aichi 464-8601, Japan) ,  Arranz Rocio (Departamento de Estructura de Macromoleculas, Centro Nacional de Biotecnologia (CNB-CSIC), Madrid 28049, Spain) ,  Valpuesta Jose M. (Departamento de Estructura de Macromoleculas, Centro Nacional de Biotecnologia (CNB-CSIC), Madrid 28049, Spain) ,  Yohda Masafumi (Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka, Koganei, Tokyo 184-8588, Japan)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 19  Issue： 8  Page： 2452  Publication year： 2018 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Prefoldin is a hexameric molec...

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Thesaurus term： substrate(biochemistry) ,  aggregation ,  atomic force microscope ,  subunit ,  *eucaryote ,  cytosol ,  interaction ,  actin ,  folding(morphology) ,  archaebacterium ,  chaperone protein ,  complex(substance) ,  substrate specificity
Semi thesaurus term： シャペロニン ,  *プレフォルディン , 【Automatic Indexing@JST】

Author keywords (6)： chaperone ,  chaperonin ,  Chaetomium thermophilum ,  proteostasis ,  interaction ,  folding

JST classification (2)： Cell physiology in general  (EF02010S) ,  Development,growth,differentiation  (EH02030U)

Reference (29)：

• Hartl, F.U.; Hayer-Hartl, M. Molecular chaperones in the cytosol: From nascent chain to folded protein. Science 2002, 295, 1852-1858.
• Gutsche, I.; Essen, L.O.; Baumeister, W. Group II chaperonins: New TRiC(k)s and turns of a protein folding machine. J. Mol. Biol. 1999, 293, 295-312.
• Horwich, A.L.; Fenton, W.A.; Chapman, E.; Farr, G.W. Two families of chaperonin: Physiology and mechanism. Annu. Rev. Cell. Dev. Biol. 2007, 23, 115-145.
• Geissler, S.; Siegers, K.; Schiebel, E. A novel protein complex promoting formation of functional alpha- and gamma-tubulin. EMBO J. 1998, 17, 952-966.
• Vainberg, I.E.; Lewis, S.A.; Rommelaere, H.; Ampe, C.; Vandekerckhove, J.; Klein, H.L.; Cowan, N.J. Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. Cell 1998, 93, 863-873.

Terms in the title (7)： 好熱性 ,  真菌 ,  コシャペロン ,  プレフォルジン ,  発現 ,  機能特性 ,  結晶化