Art

J-GLOBAL ID：201902292023201959   Reference number：19A0980667

Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3

TAK1,NF-κBおよびSTAT3のダウンレギュレーションを介したヒトトリプルネガティブ乳癌細胞に対するノル-wogonin(5, 7, 8-トリヒドロキシフラボンの抗癌効果【JST・京大機械翻訳】

Author (20)： Abd El-Hafeez Amer Ali (Pharmacotherapy Department, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Abd El-Hafeez Amer Ali (Global Career Design Center, Hiroshima University, Hiroshima, Japan) ,  Abd El-Hafeez Amer Ali (Pharmacology and Experimental Oncology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt) ,  Khalifa Hazim O. (Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt) ,  Khalifa Hazim O. (Department of Infectious Diseases, Graduate School of Medicine, International University of Health and Welfare, Narita, Japan) ,  Mahdy Elham A.M. (Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt) ,  Sharma Vikas (Pharmacology Department, Case Western Reserve University School of Medicine, Cleveland, OH, USA) ,  Hosoi Toru (Pharmacotherapy Department, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Ghosh Pradipta (Department of Medicine, University of California, San Diego, La Jolla, CA,USA) ,  Ghosh Pradipta (Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA) ,  Ghosh Pradipta (Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA) ,  Ozawa Koichiro (Pharmacotherapy Department, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Montano Monica M. (Pharmacology Department, Case Western Reserve University School of Medicine, Cleveland, OH, USA) ,  Fujimura Takashi (Hiroshima Research Center for Healthy Aging (HiHA), Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Hiroshima, Japan) ,  Ibrahim Ahmed R.N. (Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, Egypt) ,  Abdelhamid Mohamed A.A. (Department of Botany and Microbiology, Faculty of Science, Minia University, Minia Egypt) ,  Abdelhamid Mohamed A.A. (Department of Biotechnology and Bioinformatics, Korea University, Sejong, Republic of Korea) ,  Pack Seung Pil (Department of Biotechnology and Bioinformatics, Korea University, Sejong, Republic of Korea) ,  Shouman Samia A. (Pharmacology and Experimental Oncology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt) ,  Kawamoto Seiji (Hiroshima Research Center for Healthy Aging (HiHA), Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Hiroshima, Japan)
Material： Pharmacological Reports  (Pharmacol Rep)
Volume： 71  Issue： 2  Page： 289-298  Publication year： 2019 
JST Material Number： A1528A  ISSN： 1734-1140  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Nor-wogonin, a polyhydroxy fla...

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Thesaurus term： cytotoxicity ,  cyclin D1 ,  Cell Cycle ,  *breast tumor ,  *human ,  Mitochondria ,  Cell Proliferation ,  *Down-Regulation ,  *antitumor action ,  survival ratio ,  Breast ,  Apoptosis ,  tumorigenesis ,  flow cytometry ,  Caspase 3

Author keywords (5)： Breast cancer ,  Nor-wogonin ,  Apoptosis ,  Cell cycle arrest ,  Multi-target flavone

JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic neurology  (GN01020W)

Terms in the title (8)： TAK1 ,  NF-κB ,  STAT3 ,  ダウンレギュレーション ,  ヒト ,  トリプルネガティブ乳癌 ,  細胞 ,  抗癌効果