Art

J-GLOBAL ID：201902293898145696   Reference number：19A0336425

TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity

TAK1は内皮アポトーシスを予防し血管完全性を維持する【JST・京大機械翻訳】

Author (20)： Naito Hisamichi (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Iba Tomohiro (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Wakabayashi Taku (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Wakabayashi Taku (Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Tai-Nagara Ikue (Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Suehiro Jun-ichi (Department of Pharmacology and Toxicology, Kyorin University School of Medicine, 6-20-2, Shinkawa, Mitaka City, Tokyo 181-8611, Japan) ,  Jia Weizhen (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Eino Daisuke (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Sakimoto Susumu (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Sakimoto Susumu (Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Muramatsu Fumitaka (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Kidoya Hiroyasu (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Sakurai Hiroyuki (Department of Pharmacology and Toxicology, Kyorin University School of Medicine, 6-20-2, Shinkawa, Mitaka City, Tokyo 181-8611, Japan) ,  Satoh Takashi (Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Satoh Takashi (Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Akira Shizuo (Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Akira Shizuo (Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Kubota Yoshiaki (Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Takakura Nobuyuki (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Takakura Nobuyuki (Laboratory of Signal Transduction, World Premier Institute Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan)
Material： Developmental Cell  (Dev Cell)
Volume： 48  Issue： 2  Page： 151-166.e7  Publication year： 2019 
JST Material Number： W1692A  ISSN： 1534-5807  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： TNF-α is a pleiotropic cytokin...

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Thesaurus term： Inflammation ,  endothelial cell ,  Mus musculus ,  tumor regression ,  *blood vessel ,  *Endothelium ,  homeostasis ,  vascular disease ,  knockout mouse ,  *Apoptosis ,  secretion (physiology) ,  TGF beta ,  myeloid cell ,  tumor ,  TNF alpha ,  *TAK1 ,  Myomorpha ,  laboratory animal

Author keywords (7)： TNF-α ,  TAK1 ,  intestinal microbiota ,  apoptosis ,  inflammation ,  vascular homeostasis ,  tumor angiogenesis

JST classification (2)： Vasculature  (EJ04030O) ,  Cell physiology in general  (EF02010S)

Terms in the title (6)： TAK1 ,  内皮 ,  アポトーシス ,  予防 ,  血管 ,  完全性