Rchr
J-GLOBAL ID：202001018017221666
Update date: Oct. 08, 2024
Macpherson Tom
Macpherson Tom | Macpherson Tom
Affiliation and department：
Job title：
Assistant Professor
Homepage URL (1)：
http://www.protein.osaka-u.ac.jp/laboratories/adbancedbrainfunctions
Research field (3)：
Animals: biochemistry, physiology, behavioral science
, Psychiatry
, Neuroscience - general
Research keywords (5)：
Striatal Pathways
, Psychiatric Disorders
, Learning and Memory
, Basal Ganglia
, Neural Networks
Research theme for competitive and other funds (6)：
Papers (27)：
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Yoshiatsu Aomine, Yuto Shimo, Koki Sakurai, Mayuka Abe, Tom Macpherson, Takaaki Ozawa, Takatoshi Hikida. Sex-dependent differences in the ability of nicotine to modulate discrimination learning and cognitive flexibility in mice. Journal of neurochemistry. 2024
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Yoshiatsu Aomine, Yoshinobu Oyama, Koki Sakurai, Tom Macpherson, Takaaki Ozawa, Takatoshi Hikida. Clozapine N-oxide, compound 21, and JHU37160 do not influence effortful reward-seeking behavior in mice. Psychopharmacology. 2023
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Tom Macpherson, Claire I. Dixon, Jonathan Robertson, Marsha M. Sindarto, Patricia H. Janak, Delia Belelli, Jeremy J. Lambert, David N. Stephens, Sarah L. King. α4-containing GABAAreceptors on DRD2-neurons of the nucleus accumbens mediate instrumental responding for conditioned reinforcers, and its potentiation by cocaine. eNeuro. 2023. ENEURO.0236-23.2023
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Suthinee Attachaipanich, Takaaki Ozawa, Tom Macpherson, Takatoshi Hikida. Dual roles for nucleus accumbens core dopamine D1-expressing neurons projecting to the substantia nigra pars reticulata in limbic and motor control in male mice. eNeuro. 2023. ENEURO.0082-23.2023
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Tadaaki Nishioka, Suthinee Attachaipanich, Kosuke Hamaguchi, Michael Lazarus, Alban de Kerchove d’Exaerde, Tom Macpherson, Takatoshi Hikida. Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior in mice. Nature Communications. 2023. 14. 1
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MISC (4)：
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柴田智弘, 米丸ひなの, 松本悠真, 中村萌, 岩本涼太郎, 尾山賀信, 櫻井航輝, MACPHERSON Tom, 疋田貴俊, 小澤貴明. The role of dopaminergic circuits on the enhancing effects of umami on salt seeking behavior in mice. 日本味と匂学会誌. 2021
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Tom Macpherson, Takatoshi Hikida. Nucleus Accumbens D1 Receptor-Expressing Neurons Control Autoshaping Behavior. NEUROPSYCHOPHARMACOLOGY. 2017. 43. S287-S287
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Takatoshi Hikida, Makiko Morita, Mahomi Kuroiwa, Tom Macpherson, Taichi Itou, Takahide Shuto, Naoki Sotogaku, Minae Niwa, Akira Sawa, Akinori Nishi. Social Isolated DISC1 Mutant Mice Displayed High Sensitivity to Chronic Cocaine Exposure and Rolipram Treatment. NEUROPSYCHOPHARMACOLOGY. 2015. 40. S249-S249
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疋田 貴俊, 森田 真規子, マクファーソン・トム, 伊藤 大一, 丹羽 美苗, 黒岩 真帆美, 澤 明, 西 昭徳. 社会的ストレス下においてDISC1変異マウスのコカイン感受性はPDE4により制御される(Cocaine-induced behavioral sensitization is regulated by PDE4 in social stressed DISC1 mutant mice). 日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集. 2015. 37回・45回. 189-189
Lectures and oral presentations (26)：
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Striatal control of cue-guided decision-making and its impairment in psychiatric conditions
(47th Annual Meeting of the Japan Neuroscience Society (JNS) 2024)
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Striatal mechanisms guiding reward, aversion, and decision-making
(Inscopix Webinar 2024)
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Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior
(Molecular and Cellular Cognition Society (MCCS) Meeting 2023)
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Striatal mechanisms of discrimination learning and their dysfunction in psychiatric conditions
(5th Annual Meeting of the UK-Japan Neuroscience Sympsoium 2023)
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Striatal mechanisms of cue-guided decision-making and its dysfunction in schizophrenia model mice
(46th Annual Meeting of the Japan Neuroscience Society (JNS) 2023)
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Education (2)：
- 2009 - 2014 Sussex University Neuroscience Behavioral and Clinical Neuroscience PhD
- 2006 - 2009 Sussex University Neuroscience Psychology and Neuroscience
Professional career (1)：
- PhD (Neuroscience) (University of Sussex, UK)
Work history (5)：
- 2020 - 現在 Osaka University Institute for Protein Research Assistant Professor
- 2018 - 2020 Osaka University Institute for Protein Research Specially Appointed Assistant Professor
- 2017 - 2018 Kyoto University Graduate School of Medicine Postdoctoral Researcher
- 2014 - 2017 Kyoto University Graduate School of Medicine JSPS Research Fellow
- 2014 - 2014 Sussex University Neuroscience Postdoctoral Researcher
Awards (3)：
- 2023/10 - Osaka University Young Investigator Award
- 2016/08 - Japan Neuroscience Society JNS-SfN Exchange Travel Award
- 2013/07 - UK Medical Research Council Centenary Early Career Award
Association Membership(s) (3)：
Society for Neuroscience
, The Physiological Society of Japan
, The Japan Neuroscience Society
