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J-GLOBAL ID：202002212292180619   Reference number：20A0108425

Polyborane-encapsulated PEGylated Liposomes Prepared Using Post-insertion Technique for Boron Neutron Capture Therapy

ホウ素中性子捕捉療法のためのPost insertion法を用いて調製したポリボラン封入PEG化リポソーム

Author (7)： Takeuchi Issei (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Takeuchi Issei (Center for Drug Delivery Research, Tokyo University of Science) ,  Kanno Yuudai (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Uchiro Hiromi (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Uchiro Hiromi (Center for Drug Delivery Research, Tokyo University of Science) ,  Makino Kimiko (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Makino Kimiko (Center for Drug Delivery Research, Tokyo University of Science)
Material： Journal of Oleo Science  (J Oleo Sci)
Volume： 68  Issue： 12  Page： 1261-1270(J-STAGE)  Publication year： 2019 
JST Material Number： G0238A  ISSN： 1345-8957  CODEN： JOSOAP  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Neutron Capture Therapy ,...
Semi thesaurus term： *PEG-coated liposome ,...

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Author keywords (5)： post-insertion ,  PEGylated liposomes ,  polyborane ,  biodistribution ,  boron neutron capture therapy

JST classification (3)： Manufacturing of fat and oil  (YG01030E) ,  Radiotherapy for tumors  (GE03034K) ,  Basic biopharmacy  (GY01021U)

Reference (35)：

• 1) Hawthorne, M.F.; Shelly, K. Liposomes as drug delivery vehicles for boron agents. J. Neuro-Oncol. 33, 53-58 (1997).
• 2) Kolate, A.; Baradia, D.; Patil, S.; Vhora, I.; Kore, G.; Misra, A. PEG - A versatile conjugating ligand for drugs and drug delivery systems. J. Controlled Rel. 192, 67-81 (2014).
• 3) Allen, T.M.; Hansen, C. Pharmacokinetics of stealth versus conventional liposomes: effect of dose. Biochim. Biophys. Acta 1068, 133-141 (1991).
• 4) Lozano, N.; Al-Ahmady, Z.S.; Beziere, N.S; Ntziachristos, V.; Kostarelos, K. Monoclonal antibody-targeted PEGylated liposome-ICG encapsulating doxorubicin as a potential theranostic agent. Int. J. Pharm. 482, 2-10 (2015).
• 5) Yoshino, K.; Nakamura, K.; Terajima, Y.; Kurita, A.; Matsuzaki, T.; Yamashita, K.; Isozaki, M.; Kasukawa, H. Comparative studies of irinotecan-loaded polyethylene glycol-modified liposomes prepared using different PEG-modification methods. Biochim. Biophys. Acta 1818, 2901-2907 (2012).

Terms in the title (6)： ホウ素中性子捕捉療法 ,  調製 ,  ポリボラン ,  封入 ,  PEG化 ,  リポソーム