Art

J-GLOBAL ID：202002212628956458   Reference number：20A0209233

Highly sensitive detection of GATA1 mutations in patients with myeloid leukemia associated with Down syndrome by combining Sanger and targeted next generation sequencing

Sangerと標的次世代シークエンシングの組み合わせによるダウン症候群と関連した骨髄性白血病患者におけるGATA1変異の高感度検出【JST・京大機械翻訳】

Author (17)： Terui Kiminori (Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Terui Kiminori (Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan) ,  Toki Tsutomu (Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Taga Takashi (Department of Pediatrics, Shiga University of Medical Science, Otsu, Japan) ,  Iwamoto Shotaro (Department of Pediatrics, Mie University Graduate School of Medicine, Tsu, Japan) ,  Miyamura Takako (Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan) ,  Hasegawa Daisuke (Department of Pediatrics, St Luke’s International Hospital, Tokyo, Japan) ,  Moritake Hiroshi (Division of Pediatrics, Department of Reproductive and Developmental Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan) ,  Hama Asahito (Department of Hematology and Oncology, Children’s Medical Center, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan) ,  Nakashima Kentaro (Department of Pediatrics, Kyushu University Graduate School of Medicine, Fukuoka, Japan) ,  Kanezaki Rika (Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Kudo Ko (Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Saito Akiko M. (Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan) ,  Horibe Keizo (Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan) ,  Adachi Souichi (Department of Human Health Sciences, Kyoto University, Kyoto, Japan) ,  Tomizawa Daisuke (Division of Leukemia and Lymphoma, Children’s Cancer Center, National Center for Child Health and Development, Tokyo, Japan) ,  Ito Etsuro (Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan)
Material： Genes, Chromosomes & Cancer  (Genes Chromosomes Cancer)
Volume： 59  Issue： 3  Page： 160-167  Publication year： 2020 
JST Material Number： T0902A  ISSN： 1045-2257  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Myeloid leukemia associated wi...

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Thesaurus term： peripheral blood ,  acute myeloid leukemia ,  myelofibrosis ,  screening (inspection) ,  child ,  targeting ,  myelocytic leukemia ,  high sensitivity ,  *Bone Marrow ,  cDNA ,  Mutation ,  *Down Syndrome ,  lymphoma ,  *GATA1 Transcription Factor ,  *next generation sequencing

Author keywords (6)： down syndrome ,  GATA1 ,  mutation ,  myeloid leukemia ,  next generation sequencing ,  sanger sequencing

JST classification (2)： Structure and chemistry of genes  (EC02020U) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Terms in the title (9)： 標的 ,  次世代シークエンシング ,  組み合わせ ,  ダウン症候群 ,  骨髄性白血病 ,  患者 ,  GATA1 ,  変異 ,  高感度