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J-GLOBAL ID：202002212804654100   Reference number：20A1174796

An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development

NFIL3-ZEB2-Id2経路はCdc1発生時にIRF8エンハンサースイッチングを妨害する【JST・京大機械翻訳】

Author (23)： Bagadia Prachi (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Huang Xiao (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Liu Tian-Tian (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Liu Tian-Tian (Howard Hughes Medical Institute, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Durai Vivek (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Grajales-Reyes Gary E. (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Nitschke Maximilian (Research Biology, Genentech, South San Francisco, CA, USA) ,  Modrusan Zora (Department of Molecular Biology, Genentech, South San Francisco, CA, USA) ,  Granja Jeffrey M. (Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA) ,  Granja Jeffrey M. (Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA) ,  Granja Jeffrey M. (Biophysics Program, Stanford University School of Medicine, Stanford, CA, USA) ,  Satpathy Ansuman T. (Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA) ,  Satpathy Ansuman T. (Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA) ,  Briseno Carlos G. (Department of Oncology, Amgen Inc., South San Francisco, CA, USA) ,  Gargaro Marco (Department of Experimental Medicine, University of Perugia, Perugia, Italy) ,  Iwata Arifumi (Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan) ,  Kim Sunkyung (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Chang Howard Y. (Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA) ,  Chang Howard Y. (Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA) ,  Shaw Andrey S. (Research Biology, Genentech, South San Francisco, CA, USA) ,  Murphy Theresa L. (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Murphy Kenneth M. (Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA) ,  Murphy Kenneth M. (Howard Hughes Medical Institute, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA)
Material： Nature Immunology  (Nat Immunol)
Volume： 20  Issue： 9  Page： 1174-1185  Publication year： 2019 
JST Material Number： W1330A  ISSN： 1529-2908  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Classical type 1 den...

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Thesaurus term： RNA ,  heredity ,  cluster ,  T cell ,  precursor(substance) ,  dendritic cell ,  *transcription factor ,  tumor immunity ,  molecular switch
Semi thesaurus term： 転写開始部位 ,  形質細胞様樹状細胞 ,  単一細胞 ,  前駆細胞 ,  遺伝子ネットワーク ,  *ZEB2 , 【Automatic Indexing@JST】

JST classification (1)： Immunological reaction in general  (ED03010T)

Terms in the title (7)： ZEB2 ,  Id2 ,  経路 ,  cDC1 ,  IRF8 ,  スイッチング ,  妨害