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J-GLOBAL ID：202002219717672580   Reference number：20A0886256

Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity

Shank2はApkCに結合し,上皮細胞極性確立中のRap1シグナル伝達と密着結合形成を制御する【JST・京大機械翻訳】

Author (14)： Sasaki Kazunori (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Kojitani Noriko (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Hirose Hiroko (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Yoshihama Yohei (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Yoshihama Yohei (Department of Animal Resource Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan) ,  Suzuki Hidefumi (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Shimada Miho (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Takayanagi Ayumi (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Takayanagi Ayumi (Department of Medical and Life Science, Graduate School of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Yamashita Akio (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Nakaya Masa-aki (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Hirano Hisashi (Advanced Medical Research Center, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Takahashi Hidehisa (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan) ,  Ohno Shigeo (Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan)
Material： Cell Reports
Volume： 31  Issue： 1  Page： Null  Publication year： 2020 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Epithelial cells establish api...

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Thesaurus term： *epithelium ,  *epithelial cell ,  polarization (phenomenon) ,  basis ,  complex (substance) ,  GTPase ,  polarity ,  binding site ,  domain structure ,  isoform ,  *Cell Polarity ,  *aPKC ,  *Tight Junctions ,  *Signal Transduction ,  *membrane and film ,  *histomembrane
Semi thesaurus term： *cellular signal transduction ,  局在化 , 【Automatic Indexing@JST】

Author keywords (7)： cell polarity ,  tight junction ,  aPKC-PAR complex ,  Shank2 ,  Rap1 ,  SPN domain ,  ankyrin repeats

JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Terms in the title (6)： aPKC ,  上皮 ,  細胞極性 ,  Rap1 ,  シグナル伝達 ,  密着結合