Art

J-GLOBAL ID：202002221012359320   Reference number：20A0626962

MCC950, a Selective Inhibitor of NLRP3 Inflammasome, Reduces the Inflammatory Response and Improves Neurological Outcomes in Mice Model of Spinal Cord Injury

NLRP3インフラマソームの選択的阻害剤,MCC950は脊髄損傷のマウスモデルにおける炎症反応を減少させ,神経学的転帰を改善する【JST・京大機械翻訳】

Author (5)： Jiao Jianhang (Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China) ,  Zhao Guanjie (Department of Kidney Medicine, China-Japan Union Hospital of Jilin University, Changchun, China) ,  Wang Yang (Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China) ,  Ren Pengfei (Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China) ,  Wu Minfei (Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China)
Material： Frontiers in Molecular Biosciences (Web)
Volume： 7  Page： 37  Publication year： 2020 
JST Material Number： U7081A  ISSN： 2296-889X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Spinal cord injury (SCI) is a ...

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Thesaurus term： *spinal cord ,  complex(substance) ,  inflammatory cytokine ,  *spinal cord injury ,  prognosis ,  grasping power ,  pharmacological action ,  neuron ,  in vitro experiment ,  therapeutic planning ,  lipopolysaccharide ,  protein ,  TNF alpha
Semi thesaurus term： *炎症反応 ,  *インフラマソーム , 【Automatic Indexing@JST】

Author keywords (5)： spinal cord injury ,  MCC950 ,  NLRP3 ,  functional recovery ,  inflammatory response

JST classification (2)： Gene expression  (EC02040Q) ,  Biological function  (EB03040U)

Reference (48)：

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Terms in the title (6)： NLRP3インフラマソーム ,  阻害剤 ,  脊髄損傷 ,  マウスモデル ,  炎症反応 ,  神経学的転帰