Art

J-GLOBAL ID：202002226047567697   Reference number：20A1007071

A chemically stable peptide agonist to neuromedin U receptor type 2

ニューロメジンU受容体2型に対する化学的に安定なペプチドアゴニスト【JST・京大機械翻訳】

Author (14)： Takayama Kentaro (Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Takayama Kentaro (Department of Environmental Biochemistry, Kyoto Pharmaceutical University, 5 Misasaginakauchi-cho, Yamashina, Kyoto 607-8414, Japan) ,  Mori Kenji (Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe-Shimmachi, Suita, Osaka 564-8565, Japan) ,  Tanaka Akiko (Laboratory of Pharmaceutical Technology, Kobe Pharmaceutical University, 4-19-1 Motoyamakitamachi, Higashinada, Kobe, Hyogo 658-8558, Japan) ,  Sasaki Yu (Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Sohma Yuko (Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Taguchi Akihiro (Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Taniguchi Atsuhiko (Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Sakane Toshiyasu (Laboratory of Pharmaceutical Technology, Kobe Pharmaceutical University, 4-19-1 Motoyamakitamachi, Higashinada, Kobe, Hyogo 658-8558, Japan) ,  Yamamoto Akira (Department of Biopharmaceutics, Kyoto Pharmaceutical University, 5 Misasaginakauchi-cho, Yamashina, Kyoto 607-8414, Japan) ,  Miyazato Mikiya (Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe-Shimmachi, Suita, Osaka 564-8565, Japan) ,  Minamino Naoto (Omics Research Center, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka 564-8565, Japan) ,  Kangawa Kenji (Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe-Shimmachi, Suita, Osaka 564-8565, Japan) ,  Hayashi Yoshio (Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan)
Material： Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)
Volume： 28  Issue： 10  Page： Null  Publication year： 2020 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Neuromedin U (NMU) is a peptid...

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Thesaurus term： *peptide ,  *receptor ,  Appetite ,  biological activity ,  *neuromedin U ,  hexapeptide ,  chemical stability ,  acyl migration ,  phosphate buffer solution ,  alcohol ,  sulfonic acid ,  nitrogen heterocyclic compound
Semi thesaurus term： *アゴニスト ,  残基 , 【Automatic Indexing@JST】

Author keywords (5)： Agonist ,  Neuromedin U receptor type 2 ,  Peptide ,  Chemical stability ,  Good’s buffer

JST classification (2)： Receptors on cell membrane  (EF04030C) ,  Synthesis of drugs  (GV01030F)

Substance index (1)： HEPES

Terms in the title (3)： ニューロメジンU ,  受容体 ,  化学