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J-GLOBAL ID：202002227623186284   Reference number：20A1005991

DGKζ depletion attenuates HIF-1α induction and SIRT1 expression, but enhances TAK1-mediated AMPKα phosphorylation under hypoxia

DGKζ枯渇はHIF-1α誘導とSIRT1発現を減衰させるが,低酸素下でのTAK1仲介AMPKαリン酸化を増強する【JST・京大機械翻訳】

Author (7)： Akimoto Ryo (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Akimoto Ryo (Department of Anesthesiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Tanaka Toshiaki (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Nakano Tomoyuki (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Hozumi Yasukazu (Department of Cell Biology and Morphology, Akita University Graduate School of Medicine, Akita 010-8543, Japan) ,  Kawamae Kaneyuki (Department of Anesthesiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Goto Kaoru (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan)
Material： Cellular Signalling  (Cell Signal)
Volume： 71  Page： Null  Publication year： 2020 
JST Material Number： T0667A  ISSN： 0898-6568  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cells cope with environmental ...

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Thesaurus term： enzyme ,  phosphatidic acid ,  *phosphorylation ,  ischemia ,  *oxygen deficiency ,  diglyceride ,  Cell Death ,  Diacylglycerol Kinase ,  *AMP-Activated Protein Kinases ,  *TAK1 ,  energy homeostasis ,  kinase
Semi thesaurus term： 脆弱性 , 【Automatic Indexing@JST】

Author keywords (5)： AMPKα ,  DGKζ ,  Energy homeostasis ,  HIF-1α ,  Hypoxia

JST classification (2)： Enzyme in general  (EB09010D) ,  Cell physiology in general  (EF02010S)

Terms in the title (13)： DGK ,  枯渇 ,  HIF-1α ,  誘導 ,  SIRT1 ,  発現 ,  減衰 ,  低酸素 ,  TAK1 ,  仲介 ,  AMPK ,  リン酸化 ,  増強