Art

J-GLOBAL ID：202002228461401132   Reference number：20A0021548

Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice

選択的SGLT1阻害剤,KGA-2727前処理はマウスにおける心筋梗塞誘発性心室リモデリングおよび心不全を防護する

Author (9)： Sawa Yohei (Division of Molecular and Cellular Pharmacology, Department of Pathophysiology and Pharmacology, Iwate Medical University School of Pharmaceutical Sciences, Iwate 028-3694, Japan) ,  Sawa Yohei (Division of Cardiology, Department of Internal Medicine, Iwate Medical University, School of Medicine, Iwate, Japan) ,  Saito Maki (Division of Molecular and Cellular Pharmacology, Department of Pathophysiology and Pharmacology, Iwate Medical University School of Pharmaceutical Sciences, Iwate 028-3694, Japan) ,  Ishida Nanae (Division of Molecular and Cellular Pharmacology, Department of Pathophysiology and Pharmacology, Iwate Medical University School of Pharmaceutical Sciences, Iwate 028-3694, Japan) ,  Ibi Miho (Department of Pathology, Iwate Medical University School of Dentistry, Iwate 028-3694, Japan) ,  Matsushita Naoko (Division of Cardiology, Department of Internal Medicine, Iwate Medical University, School of Medicine, Iwate, Japan) ,  Morino Yoshihiro (Division of Cardiology, Department of Internal Medicine, Iwate Medical University, School of Medicine, Iwate, Japan) ,  Taira Eiichi (Department of Pharmacology, Iwate Medical University School of Medicine, Iwate, Japan) ,  Hirose Masamichi (Division of Molecular and Cellular Pharmacology, Department of Pathophysiology and Pharmacology, Iwate Medical University School of Pharmaceutical Sciences, Iwate 028-3694, Japan)
Material： Journal of Pharmacological Sciences (Web)  (J Pharmacol Sci (Web))
Volume： 142  Issue： 1  Page： 16-25  Publication year： 2020 
JST Material Number： U0667A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： ratio ,...
Semi thesaurus term： *SGLT1 ,...

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Author keywords (5)： Sodium/glucose co-transporter 1 ,  Myocardial infarction ,  Cardiomyocyte hypertrophy ,  Myocardial fibrosis ,  Heart failure

JST classification (2)： Basic medicine on cardiovascular system  (GJ01020K) ,  Basic research of cardioactive drugs  (GW07020N)

Substance index (1)： KGA-2727

Terms in the title (8)： SGLT1 ,  阻害剤 ,  前処理 ,  マウス ,  心筋梗塞 ,  心室リモデリング ,  心不全 ,  防護