Art

J-GLOBAL ID：202002228726591168   Reference number：20A0116893

Evaluation of the Water Content and Skin Permeability of Active Pharmaceutical Ingredients in Ketoprofen Poultice Formulations Removed from Their Airtight Containers and Left at Room Temperature

気密容器から取り出し室温で放置したケトプロフェン湿布製剤中の活性医薬品成分の含水量と皮膚透過性の評価

Author (6)： Yamamoto Yoshihisa (Unit of Physical Pharmaceutics, Faculty of Pharmaceutical Sciences, Teikyo Heisei University) ,  Yamauchi Rie (Division of Pharmaceutical Education and Research, Hoshi University) ,  Ohno Shuji (Division of Pharmaceutical Education and Research, Hoshi University) ,  Asai Kazunori (Division of Pharmaceutical Education and Research, Hoshi University) ,  Fukami Toshiro (Department of Molecular Pharmaceutics, Meiji Pharmaceutical University) ,  Koide Tatsuo (Division of Drugs, National Institute of Health Sciences)
Material： Biological and Pharmaceutical Bulletin (Web)
Volume： 42  Issue： 12  Page： 2102-2108(J-STAGE)  Publication year： 2019 
JST Material Number： U1402A  ISSN： 1347-5215  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cataplasm ,...
Semi thesaurus term： cutaneous permeability

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Author keywords (10)： ketoprofen ,  poultice ,  adhesive polymer layer ,  skin permeability ,  water ,  ketoprofen ,  poultice ,  adhesive polymer layer ,  skin permeability ,  water

JST classification (1)： Pharmaceutical preparations in general  (GY02010Z)

Substance index (1)： Ketoprofen

Reference (14)：

• 1) Chien YW. Transdermal drug delivery and delivery system. Novel Drug Delivery Systems. Vol. 50, Marcel Dekker, New York, pp. 301-380 (1992).
• 2) Subedi RK, Oh SY, Chun MK, Choi HK. Recent advances in transdermal drug delivery. Arch. Pharm. Res., 33, 339-351 (2010).
• 3) Kawamura N, Shinkai N, Yamauchi H, Takayama S. Comparison of poultice-type and tape-type patches containing ketoprofen on human skin irritation. J. Toxicol. Sci., 28, 415-425 (2003).
• 4) Wester RC, Mainbach HI. Regional variation in percutaneous absorption. Percutaneous absorption. (Bronaugh RL, Maibach HI, eds.) Vol. 97, Marcel Dekker, New York, pp. 107-132 (1999).
• 5) Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, Vane JR. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc. Natl. Acad. Sci. U.S.A., 96, 7563-7568 (1999).

Terms in the title (11)： 気密容器 ,  取り出し ,  室温 ,  ケトプロフェン ,  湿布 ,  製剤 ,  活性 ,  医薬品 ,  含水量 ,  皮膚透過性 ,  評価