Art

J-GLOBAL ID：202002229777603281   Reference number：20A0558462

Oxidation of NAC in DMSO solvent in ADRA and its effect on sensitization prediction accuracy

ADRAにおけるDMSO溶媒中でのNAC酸化および感作予測精度に対するその影響

Author (18)： AKIMOTO Miyuki (FUJIFILM Corp., Kanagawa, JPN) ,  YOSHIDA Kousuke (Lion Corp., Kanagawa, JPN) ,  WATANABE Shinichi (Lion Corp., Kanagawa, JPN) ,  YAMAGA Hiroaki (Lion Corp., Kanagawa, JPN) ,  WAKABAYASHI Koji (MITSUI CHEMICALS, INC., Chiba, JPN) ,  TAHARA Yu (MITSUI CHEMICALS, INC., Chiba, JPN) ,  HORIE Nobuyuki (SUMITOMO Chemical Co., Ltd., Osaka, JPN) ,  FUJIMOTO Keiichi (SUMITOMO Chemical Co., Ltd., Osaka, JPN) ,  KUSAKARI Kei (NISSAN CHEMICAL Corp., Saitama, JPN) ,  KAMIYA Kohei (NISSAN CHEMICAL Corp., Saitama, JPN) ,  KAWAKAMI Tsuyoshi (National Inst. Health Sci., Tokyo, JPN) ,  KOJIMA Kohichi (Food and Drug Safety Center, Kanagawa, JPN) ,  SOZU Takashi (Tokyo Univ. Sci., Tokyo, JPN) ,  ONO Atsushi (Okayama Univ., Okayama, JPN) ,  KOJIMA Hajime (National Inst. Health Sci., Tokyo, JPN) ,  FUJITA Masaharu (FUJIFILM Corp., Kanagawa, JPN) ,  YAMAMOTO Yusuke (FUJIFILM Corp., Kanagawa, JPN) ,  KASAHARA Toshihiko (FUJIFILM Corp., Kanagawa, JPN)
Material： Alternatives to Animal Testing and Experimentation  (AATEX)
Volume： 24  Issue： Supplement  Page： 179  Publication year： Dec. 31, 2019 
JST Material Number： L5507A  ISSN： 1344-0411  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： solvent ,...
Semi thesaurus term： *ADRA ,...

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JST classification (2)： Bioassay  (EA03060N) ,  Other effects on organic reaction  (CF02120K)

Substance index (3)： Dimethyl sulfoxide ,  Acetylcysteine ,  Acetonitrile

Terms in the title (7)： ADRA ,  DMSO ,  溶媒 ,  NAC ,  酸化 ,  感作 ,  予測精度