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J-GLOBAL ID：202002234561893263   Reference number：20A1082455

Induction of enantio-selective apoptosis in human leukemia HL-60 cells by (S)-erypoegin K, an isoflavone isolated from Erythrina poeppigiana

Erythrina Poeppigianaから単離したイソフラボン,(S)-eryポギンKによるヒト白血病HL-60細胞におけるエナンチオ選択的アポトーシスの誘導【JST・京大機械翻訳】

Author (12)： Hikita Kiyomi (Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Saigusa Satomi (Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Takeuchi Yuto (Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Matsuyama Haruka (Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Nagai Rina (Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Kato Kuniki (Laboratory of Natural Product, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Murata Tomiyasu (Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Tanaka Hitoshi (Laboratory of Natural Product, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan) ,  Wagh Yogesh S. (Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan) ,  Asao Naoki (Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan) ,  Asao Naoki (Division of Chemistry and Materials, Graduate School of Science and Technology, Shinshu University, Ueda, Nagano 386-8567, Japan) ,  Kaneda Norio (Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya 468-8503, Japan)
Material： Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)
Volume： 28  Issue： 11  Page： Null  Publication year： 2020 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Erypoegin K, an isoflavone iso...

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Thesaurus term： bark ,  antitumor drug ,  *Leukemia ,  human ,  genome ,  high performance liquid chromatography ,  isomer (molecule) ,  *Apoptosis ,  Caspase 3 ,  apoptosis induction ,  DNA ladder ,  *Erythrina ,  aliphatic aldehyde ,  aliphatic ketone ,  nitrogen heterocyclic compound ,  quinolizidine alkaloid ,  bridged compound ,  ketone ,  oxygen heterocyclic compound ,  isoflavonoid ,  polynuclear aromatic compound
Semi thesaurus term： *Erythrina , 【Automatic Indexing@JST】

Author keywords (6)： Isoflavone ,  Erypoegin K ,  Anti-proliferative activity ,  Enantio-selective apoptosis induction ,  Anti-tumor agent ,  HL-60 cell

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Synthesis of drugs  (GV01030F)

Substance index (3)： Methylglyoxal ,  Genisteine ,  Isoflavone

Terms in the title (8)： Erythrina ,  単離 ,  イソフラボン ,  ヒト ,  白血病 ,  HL-60細胞 ,  アポトーシス ,  誘導