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J-GLOBAL ID：202002234691942722   Reference number：20A1471849

Improvement of the dP-nucleoside-mediated herpes simplex virus thymidine kinase negative-selection system by manipulating dP metabolism genes

dP代謝遺伝子操作によるdP-ヌクレオシド仲介単純ヘルペスウイルスチミジンキナーゼのネガティブ選択系の改良

Author (6)： Kawai-Noma Shigeko (Department of Applied Chemistry and Biotechnology, Chiba University, Chiba 263-8522, Japan) ,  Saeki Kazuya (Department of Applied Chemistry and Biotechnology, Chiba University, Chiba 263-8522, Japan) ,  Yumoto Tatsuya (Department of Applied Chemistry and Biotechnology, Chiba University, Chiba 263-8522, Japan) ,  Minakata Katsuya (Department of Applied Chemistry and Biotechnology, Chiba University, Chiba 263-8522, Japan) ,  Saito Kyoichi (Department of Applied Chemistry and Biotechnology, Chiba University, Chiba 263-8522, Japan) ,  Umeno Daisuke (Department of Applied Chemistry and Biotechnology, Chiba University, Chiba 263-8522, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 130  Issue： 2  Page： 121-127  Publication year： Aug. 2020 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *screening (inspection) ,...
Semi thesaurus term： genetic regulation ,...

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Author keywords (5)： Negative selection system ,  Mutagenic nucleoside analog 6-(β-d-2-deoxyribofuranosyl)-3 4-dihydro-8H-pyrimido [4 5-c][1 2] oxazin-7-one ,  Herpes simplex virus thymidine kinase ,  Genome engineering ,  Escherichia coli

JST classification (2)： Gene manipulation  (EC02050B) ,  Microorganism physiology in general  (EG03051L)

Substance index (1)： 6-(2-Deoxy-β-D-ribofuranosyl)-2-oxa-1,6,8-triazadecalin-4a(5),8-diene-7-one

Terms in the title (7)： DP ,  代謝 ,  遺伝子操作 ,  ヌクレオシド ,  仲介 ,  単純ヘルペスウイルス ,  チミジンキナーゼ