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J-GLOBAL ID：202002239667318751   Reference number：20A2772878

Structural Basis for the Binding Mechanism of Human Serum Albumin Complexed with Cyclic Peptide Dalbavancin

環状ペプチドダルババンシンと複合体を形成したヒト血清アルブミンの結合機構の構造的基礎【JST・京大機械翻訳】

Author (11)： Ito Sho (ROD (Single Crystal Analysis) Group, Application Laboratories, Rigaku Corporation, Tokyo, Japan) ,  Ito Sho (Graduate School of Life Science, University of Hyogo, Hyogo, Japan) ,  Senoo Akinobu (Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan) ,  Nagatoishi Satoru (Institute of Medical Science, The University of Tokyo, Tokyo, Japan) ,  Ohue Masahito (Department of Computer Science, School of Computing, Tokyo Institute of Technology, Kanagawa, Japan) ,  Yamamoto Masaki (RIKEN SPring-8 Center, Hyogo, Japan) ,  Yamamoto Masaki (Graduate School of Life Science, University of Hyogo, Hyogo, Japan) ,  Tsumoto Kouhei (Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan) ,  Tsumoto Kouhei (Institute of Medical Science, The University of Tokyo, Tokyo, Japan) ,  Tsumoto Kouhei (Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan) ,  Wakui Naoki (Department of Electrical and Electronic Systems Engineering, National Institute of Technology, Nagaoka College, Niigata, Japan)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 63  Issue： 22  Page： 14045-14053  Publication year： 2020 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Cyclic peptides, with unique s...

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Thesaurus term： crystal structure ,  interaction ,  half-life ,  structure analysis ,  monomer ,  *cyclopeptide ,  binding site ,  *complex(substance) ,  structural property ,  drug delivery system
Semi thesaurus term： 非共有結合 ,  分子動力学シミュレーション ,  *ヒト血清アルブミン ,  等温滴定熱量測定 ,  誘導適合 , 【Automatic Indexing@JST】

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Peptides  (CF10080G)

Terms in the title (5)： 環状ペプチド ,  ダルババンシン ,  複合体 ,  ヒト血清アルブミン ,  基礎