Art

J-GLOBAL ID：202002240692916411   Reference number：20A2062100

L-type amino acid transporter 1, LAT1, in growth hormone-producing pituitary tumor cells

成長ホルモン産生下垂体腫瘍細胞におけるL型アミノ酸輸送体1,LAT1【JST・京大機械翻訳】

Author (13)： Satou Motoyasu (Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada) ,  Satou Motoyasu (Department of Biochemistry, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan) ,  Wang Jason (Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada) ,  Nakano-Tateno Tae (Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada) ,  Teramachi Mariko (Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada) ,  Suzuki Tokiko (J-Pharma Co., Ltd., Yokohama Kanagawa, Japan) ,  Hayashi Keitaro (Department of Pharmacology and Toxicology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan) ,  Lamothe Shawn (Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada) ,  Hao Yubin (Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada) ,  Kurata Harley (Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada) ,  Sugimoto Hiroyuki (Department of Biochemistry, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan) ,  Chik Constance (Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada) ,  Tateno Toru (Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada)
Material： Molecular and Cellular Endocrinology  (Mol Cell Endocrinol)
Volume： 515  Page： Null  Publication year： 2020 
JST Material Number： D0025B  ISSN： 0303-7207  CODEN： MCEND6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Pituitary tumors (PTs) can cau...

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Thesaurus term： mRNA ,  Heredity ,  *pituitary gland ,  Mortality ,  *tumor cell ,  *growth hormone ,  *hormone ,  Rattus ,  Cell Proliferation ,  ablation ,  Down-Regulation ,  Apoptosis ,  Myomorpha ,  aliphatic amine ,  aliphatic carboxylic acid ,  branched-chain amino acid ,  ether ,  macrocyclic compound ,  lactam ,  lactone ,  enzyme inhibitor ,  hemiacetal ,  alicyclic alcohol ,  secondary alcohol ,  hydroxy ketone
Semi thesaurus term： 治療標的 , 【Automatic Indexing@JST】

Author keywords (4)： L-type amino acid transporter 1 (LAT1) ,  Pituitary tumor ,  Targeted therapy ,  mTOR

JST classification (2)： Transport of cell membrane  (EF04020R) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (2)： Leucine ,  Sirolimus

Terms in the title (5)： 成長ホルモン ,  下垂体 ,  腫瘍細胞 ,  L型アミノ酸輸送体1 ,  LAT1