Art

J-GLOBAL ID：202002243657815969   Reference number：20A0995178

Acetaminophen-induced hepatotoxicity of cultured hepatocytes depends on timing of isolation from light-cycle controlled mice

培養されている肝細胞のアセトアミノフェン誘発肝毒性は,光周期を制御されているマウスからの単離のタイミングに依存する

Author (7)： Moriya Koji (Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama-shi, Japan) ,  Tamai Miho (Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama-shi, Japan) ,  Tamai Miho (Faculty of Dental Medicine, Hokkaido University, Sapporo, Japan) ,  Koga Takumi (School of Life Science and Technology, Tokyo Institute of Technology, Yokohama-shi, Japan) ,  Tanaka Toshiaki (School of Life Science and Technology, Tokyo Institute of Technology, Yokohama-shi, Japan) ,  Tagawa Yoh-ichi (Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama-shi, Japan) ,  Tagawa Yoh-ichi (School of Life Science and Technology, Tokyo Institute of Technology, Yokohama-shi, Japan)
Material： Genes to Cells  (Genes Cells)
Volume： 25  Issue： 4  Page： 257-269  Publication year： Apr. 2020 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： antipyretic analgesic ,...
Semi thesaurus term： primary cultured hepatocytes

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Author keywords (5)： acetaminophen-induced hepatotoxicity ,  circadian rhythm ,  culture model ,  hepatic function ,  metabolism

JST classification (3)： Animal physiology in general  (EJ02010E) ,  Toxicity of chemical substances in general  (GZ02010C) ,  Basic research of antipyretic analgesics  (GW03040H)

Substance index (2)： Glutathione ,  Acetaminophen

Terms in the title (8)： 培養 ,  肝細胞 ,  アセトアミノフェン ,  誘発 ,  肝毒性 ,  光周期 ,  マウス ,  単離