Art

J-GLOBAL ID：202002244745861018   Reference number：20A0553591

Relationships between plasma lactate, plasma alanine, genetic variations in lactate transporters and type 2 diabetes in the Japanese population

日本人集団における血漿乳酸,血漿アラニン,乳酸輸送体の遺伝的変異と2型糖尿病の間の関係

Author (10)： Higuchi Issei (Department of Pharmacy, Hokkaido University Hospital, Kita-14-jo, Nishi-5-chome, Kita-ku, Sapporo, 060-8648, Japan) ,  Kimura Yuki (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo, 060-0812, Japan) ,  Kobayashi Masaki (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo, 060-0812, Japan) ,  Narumi Katsuya (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo, 060-0812, Japan) ,  Furugen Ayako (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo, 060-0812, Japan) ,  Miyoshi Hideaki (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15-jo, Nishi-7-chome, Kita-ku, Sapporo, 060-8638, Japan) ,  Nakamura Akinobu (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15-jo, Nishi-7-chome, Kita-ku, Sapporo, 060-8638, Japan) ,  Yamada Takehiro (Department of Pharmacy, Hokkaido University Hospital, Kita-14-jo, Nishi-5-chome, Kita-ku, Sapporo, 060-8648, Japan) ,  Atsumi Tatsuya (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15-jo, Nishi-7-chome, Kita-ku, Sapporo, 060-8638, Japan) ,  Iseki Ken (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo, 060-0812, Japan)
Material： Drug Metabolism and Pharmacokinetics (Web)  (Drug Metab Pharmacokinet (Web))
Volume： 35  Issue： 1  Page： 131-138  Publication year： 2020 
JST Material Number： U0705A  ISSN： 1347-4367  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： MCT1 transporter

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Author keywords (5)： l-lactate ,  Diabetes ,  Monocarboxylate transporter ,  Single nucleotide polymorphism ,  Liver enzymes

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Genetic variation  (EC01030Y)

Substance index (2)： L-Lactic acid ,  Glucose

Terms in the title (8)： 日本人 ,  集団 ,  血漿 ,  乳酸 ,  アラニン ,  輸送体 ,  遺伝的変異 ,  2型糖尿病