Art

J-GLOBAL ID：202002245506653408   Reference number：20A2016271

Effects of Physical Exercise on Autophagy and Apoptosis in Aged Brain: Human and Animal Studies

老齢脳におけるオートファジーとアポトーシスに対する身体運動の効果:ヒトおよび動物研究【JST・京大機械翻訳】

Author (6)： Andreotti Diana Zukas (Laboratory of Molecular and Functional Neurobiology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil) ,  Silva Josiane do Nascimento (Laboratory of Molecular and Functional Neurobiology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil) ,  Matumoto Amanda Midori (Laboratory of Molecular and Functional Neurobiology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil) ,  Orellana Ana Maria (Laboratory of Molecular Neuropharmacology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil) ,  de Mello Paloma Segura (Laboratory of Molecular Neuropharmacology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil) ,  Kawamoto Elisa Mitiko (Laboratory of Molecular and Functional Neurobiology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil)
Material： Frontiers in Nutrition (Web)
Volume： 7  Page： 94  Publication year： 2020 
JST Material Number： U7088A  ISSN： 2296-861X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The aging process is character...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A2016271&from=J-GLOBAL&jstjournalNo=U7088A") }}

Thesaurus term： *animal ,  human(primates) ,  senile change ,  *old age ,  prevention ,  pharmacology ,  characterization ,  *apoptosis ,  *autophagy
Semi thesaurus term： *身体運動 ,  不均衡 ,  神経細胞死 ,  脳発生 , 【Automatic Indexing@JST】

Author keywords (5)： aging ,  exercise ,  autophagy ,  apoptosis ,  brain

JST classification (2)： Central nervous system  (EJ12030F) ,  Rehabilitation  (GB06000Z)

Reference (229)：

• Lopez-Otin C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. (2013) 153:1194-217. doi: 10.1016/j.cell.2013.05.039
• Kirkwood TB. Understanding the odd science of aging. Cell. (2005) 120:437-47. doi: 10.1016/j.cell.2005.01.027
• Escobar KA, Cole NH, Mermier CM, VanDusseldorp AT. Autophagy and aging: maintaining the proteome through exercise and caloric restriction. Aging Cell. (2019) 18:e12876. doi: 10.1111/acel.12876
• Bennett IJ, Madden JD. Disconnected aging: cerebral white matter integrity and age-related differences in cognition. Neuroscience. (2014) 276:187-205. doi: 10.1016/j.neuroscience.2013.11.026
• Metzler-Baddeley C, Mole JP, Sims R, Fasano F, Evans J, Jones DK, et al. Fornix white matter glia damage causes hippocampal gray matter damage during age-dependent limbic decline. Sci Rep. (2019) 9:1060. doi: 10.1038/s41598-019-51737-1

Terms in the title (9)： 老齢 ,  脳 ,  オートファジー ,  アポトーシス ,  身体 ,  運動の効果 ,  ヒト ,  動物 ,  研究