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J-GLOBAL ID：202002250443032522   Reference number：20A1336249

Functional role of c-Jun NH₂-terminal kinase-associated leucine zipper protein (JLP) in lysosome localization and autophagy

リソソーム局在とオートファジーにおけるc-Jun NH₂末端キナーゼ関連ロイシンジッパー蛋白質(JLP)の機能的役割

Author (6)： Suzuki Ryusuke (Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.) ,  Gunarta I Ketut (Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.) ,  Boldbaatar Jambaldorj (Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.) ,  Erdenebaatar Purev (Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.) ,  Odongoo Ravdandorj (Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.) ,  Yoshioka Katsuji (Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.)
Material： Drug Discoveries & Therapeutics  (DD & T)
Volume： 14  Issue： 1  Page： 35-41(J-STAGE)  Publication year： 2020 
JST Material Number： F1177A  ISSN： 1881-7831  CODEN： DDTRBX  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *lysosome ,...
Semi thesaurus term： *ロイシンジッパー蛋白質 ,...

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Author keywords (3)： dynein ,  kinesin ,  lysosomal transport

JST classification (2)： Biological function  (EB03040U) ,  Function of cell components  (EF03060C)

Reference (24)：

• 1. Pu J, Guardia CM, Keren-Kaplan T, Bonifacino JS. Mechanisms and functions of lysosome positioning. J Cell Sci. 2016; 129:4329-4339.
• 2. Cabukusta B, Neefjes J. Mechanisms of lysosomal positioning and movement. Traffic. 2018; 19:761-769.
• 3. Lawrence RE, Cho KF, Rappold R, Thrun A, Tofaute M, Kim DJ, Moldavski O, Hurley JH, Zoncu R. The lysosome as a cellular centre for signalling, metabolism and quality control. Nat Cell Biol. 2018; 20:1052-1063.
• 4. Willett R, Martina JA, Zewe JP, Wills R, Hammond GRV, Puertollano R. TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes. Nat Commun. 2017; 8:1580.
• 5. Lee CM, Onésime D, Reddy CD, Dhanasekaran N, Reddy EP. JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors. Proc Natl Acad Sci U S A. 2002; 99:14189-14194.

Terms in the title (7)： リソソーム ,  オートファジー ,  c-Jun ,  キナーゼ ,  ロイシンジッパー ,  蛋白質 ,  役割