Art

J-GLOBAL ID：202002251140994468   Reference number：20A2208127

A computational approach to explore and identify potential herbal inhibitors for the p21-activated kinase 1 (PAK1)

p21活性化キナーゼ1(PAK1)に対する潜在的薬草阻害剤の探索と同定に対する計算アプローチ【JST・京大機械翻訳】

Author (7)： Shahinozzaman Md (PAK Research Center, University of the Ryukyus, Okinawa, Japan) ,  Shahinozzaman Md (Department of Bioscience and Biotechnology, University of the Ryukyus, Okinawa, Japan) ,  Ishii Takahiro (Department of Bioscience and Biotechnology, University of the Ryukyus, Okinawa, Japan) ,  Ahmed Sinthyia (Division of Computer Aided Drug Design, The Red-Green Research Center, Dhaka, Bangladesh) ,  Halim Mohammad A. (Department of Physical Sciences, University of Arkansas-Fort Smith, Fort Smith, AR, USA) ,  Tawata Shinkichi (PAK Research Center, University of the Ryukyus, Okinawa, Japan) ,  Tawata Shinkichi (Department of Bioscience and Biotechnology, University of the Ryukyus, Okinawa, Japan)
Material： Journal of Biomolecular Structure and Dynamics
Volume： 38  Issue： 12  Page： 3514-3526  Publication year： 2020 
JST Material Number： W5935A  ISSN： 0739-1102  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Abstract: The oncogenic kinase...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A2208127&from=J-GLOBAL&jstjournalNo=W5935A") }}

Thesaurus term： simulation ,  intermolecular interaction ,  diabetes mellitus ,  *medicinal plant ,  larva of arthropoda ,  active site ,  excretion ,  bioavailability ,  molecular dynamics ,  Alzheimer disease ,  herb
Semi thesaurus term： 結合親和性 ,  AutoDock ,  治療標的 ,  *キナーゼ , 【Automatic Indexing@JST】

Author keywords (6)： p21-activated kinase 1 ,  PAK1 inhibitors ,  herbal drugs ,  nymphaeol A ,  molecular docking ,  molecular dynamics

JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Terms in the title (7)： p21活性化キナーゼ1 ,  PAK1 ,  薬草 ,  阻害剤 ,  探索 ,  同定 ,  計算