Art

J-GLOBAL ID：202002252560204542   Reference number：20A2685022

Glucose transporter 4 mediates LPS-induced IL-6 production in osteoblasts under high glucose conditions

グルコーストランスポーター4は高グルコース条件下で骨芽細胞におけるLPS誘導IL-6産生を仲介する

Author (13)： Kato Shunichiro (Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry) ,  Tanabe Natsuko (Department of Biochemistry, Nihon University School of Dentistry) ,  Tanabe Natsuko (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry) ,  Nagao Mayu (Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, and Bone and Joint Institute, Western University) ,  Sekino Jumpei (Department of Dysphagia Rehabilitation, Nihon University School of Dentistry) ,  Tomita Keiko (Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry) ,  Sakai Mayu (Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry) ,  Abe Kimiko (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry) ,  Abe Kimiko (Department of Dysphagia Rehabilitation, Nihon University School of Dentistry) ,  Suzuki Naoto (Department of Biochemistry, Nihon University School of Dentistry) ,  Suzuki Naoto (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry) ,  Ueda Koichiro (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry) ,  Ueda Koichiro (Department of Dysphagia Rehabilitation, Nihon University School of Dentistry)
Material： Journal of Oral Science  (J Oral Sci)
Volume： 62  Issue： 4  Page： 423-426(J-STAGE)  Publication year： 2020 
JST Material Number： Z0759A  ISSN： 1343-4934  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： cultured cell ,...
Semi thesaurus term： *IL6 ,...

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Author keywords (4)： glucose ,  GLUT4 ,  LPS ,  proinflammatory cytokine

JST classification (2)： Basic dentistry(= odontology)  (GT01020O) ,  Gene expression  (EC02040Q)

Substance index (1)： Glucose

Reference (32)：

• 1. Page RC (1991) The role of inflammatory mediators in the pathogenesis of periodontal disease. J Periodontal Res 26, 230-242.
• 2. Kassebaum NJ, Bernabé E, Dahiya M, Bhandari B, Murray CJL, Marcenes W (2014) Global burden of severe periodontitis in 1990-2010: a systematic review and meta- regression. J Dent Res 93, 1045-1053.
• 3. Sanz M, Ceriello A, Buysschaert M, Chapple I, Demmer RT, Graziani F et al. (2018) Scientific evidence on the links between periodontal diseases and diabetes: consensus report and guidelines of the joint workshop on periodontal diseases and diabetes by the International Diabetes Federation and the European Federation of Periodontology. Diabetes Res Clin Pract 137, 231-241.
• 4. Graziani F, Gennai S, Solini A, Petrini M (2018) A systematic review and meta-analysis of epidemiologic observational evidence on the effect of periodontitis on diabetes an update of the EFP-AAP review. J Clin Periodontol 45, 167-187.
• 5. Rhee SH (2014) Lipopolysaccharide: basic biochemistry, intracellular signaling, and physiological impacts in the gut. Intest Res 12, 90-95.

Terms in the title (7)： グルコーストランスポーター4 ,  グルコース ,  骨芽細胞 ,  LPS ,  誘導 ,  IL-6 ,  仲介