Art

J-GLOBAL ID：202002253159328310   Reference number：20A2253643

Nicotine Rescues Depressive-like Behaviors via α7-type Nicotinic Acetylcholine Receptor Activation in CaMKIV Null Mice

ニコチンはCaMKIVヌルマウスにおけるα7型ニコチン性アセチルコリン受容体活性化を介して抑鬱様行動を救済する【JST・京大機械翻訳】

Author (8)： Moriguchi Shigeki (Research Center for Pharmaceutical Development, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Moriguchi Shigeki (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Inagaki Ryo (Research Center for Pharmaceutical Development, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Inagaki Ryo (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Yi Lusha (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Shibata Mikako (Research Center for Pharmaceutical Development, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Sakagami Hiroyuki (Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Japan) ,  Fukunaga Kohji (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan)
Material： Molecular Neurobiology
Volume： 57  Issue： 12  Page： 4929-4940  Publication year： 2020 
JST Material Number： W0110A  ISSN： 0893-7648  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: The nicotinic acetyl...

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Thesaurus term： protein kinase ,  affinity ,  Calmodulin ,  dentate gyrus ,  *nicotinic receptor ,  Phosphatidylinositol 3-Kinase ,  CRE binding protein ,  Akt/protein kinase B ,  Signal Transduction ,  Hippocampus ,  fatty acid ,  nitrogen heterocyclic compound ,  drug ,  tobacco alkaloid
Semi thesaurus term： cellular signal transduction ,  BDNF ,  アゴニスト ,  アンタゴニスト , 【Automatic Indexing@JST】

Author keywords (5)： Nicotine ,  CaMKIV null mice ,  Depressive-like behaviors ,  Adult hippocampal neurogenesis ,  α7-type nAChR

JST classification (2)： Receptors on cell membrane  (EF04030C) ,  Cell physiology in general  (EF02010S)

Substance index (3)： Methyllycaconitine ,  Acetylcholine ,  Nicotine

Terms in the title (5)： ニコチン ,  CaMKIV ,  ニコチン性アセチルコリン受容体 ,  活性化 ,  鬱様行動