Art

J-GLOBAL ID：202002256288378636   Reference number：20A0646197

Inhibition of inflammation-mediated DPP-4 expression by linagliptin increases M2 macrophages in atherosclerotic lesions

リナグリプチンによる炎症媒介DPP-4発現の阻害はアテローム性動脈硬化病変におけるM2マクロファージを増加させる【JST・京大機械翻訳】

Author (11)： Nishida Shuhei (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Matsumura Takeshi (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Senokuchi Takafumi (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Murakami-Nishida Saiko (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Ishii Norio (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Morita Yutaro (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Yagi Yoshitaka (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Motoshima Hiroyuki (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Kondo Tatsuya (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Araki Eiichi (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Araki Eiichi (Center for Metabolic Regulation of Healthy Aging (CMHA), Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 524  Issue： 1  Page： 8-15  Publication year： 2020 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Dipeptidyl peptidase-4 (DPP-4)...

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Thesaurus term： *macrophage ,  diabetes mellitus ,  aorta ,  dipeptidyl aminopeptidase ,  polarization(phenomenon) ,  siRNA ,  high fat diet ,  mRNA ,  *atherosclerosis ,  *arteriosclerosis ,  filler(pharmaceuticals) ,  *inflammation ,  in vitro experiment ,  interferon gamma

Author keywords (4)： Atherosclerosis ,  Macrophage ,  Polarization ,  DPP-4 inhibitor

JST classification (4)： Function of cell components  (EF03060C) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Receptors on cell membrane  (EF04030C) ,  Gene expression  (EC02040Q)

Substance index (1)： Linagliptin

Terms in the title (8)： リナグリプチン ,  炎症 ,  DPP-4 ,  発現 ,  阻害 ,  アテローム性動脈硬化 ,  病変 ,  M2マクロファージ