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J-GLOBAL ID：202002261120849473   Reference number：20A1250521

ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism

ARE結合蛋白質ZFP36L1は脱アデニル化非依存性機構を介して翻訳を直接抑制するためにCNOT1と相互作用する【JST・京大機械翻訳】

Author (12)： Otsuka Hiroshi (Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Japan) ,  Fukao Akira (Kindai University, Higashi, Osaka, Japan) ,  Tomohiro Takumi (Laboratory of RNA Function, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Adachi Shungo (Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan) ,  Suzuki Toru (Laboratory for Immunogenetics, Center for Integrative Medical Sciences, RIKEN, 1-7-22, Suehiro-cho, Yokohama, Japan) ,  Takahashi Akinori (Cell Signal Unit, Okinawa Institute of Science and Technology, Onna-son, Kunigami-gun, Okinawa, Japan) ,  Funakami Yoshinori (Kindai University, Higashi, Osaka, Japan) ,  Natsume Toru (Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan) ,  Yamamoto Tadashi (Laboratory for Immunogenetics, Center for Integrative Medical Sciences, RIKEN, 1-7-22, Suehiro-cho, Yokohama, Japan) ,  Yamamoto Tadashi (Cell Signal Unit, Okinawa Institute of Science and Technology, Onna-son, Kunigami-gun, Okinawa, Japan) ,  Duncan Kent E. (Neuronal Translational Control Group, Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ,  Fujiwara Toshinobu (Kindai University, Higashi, Osaka, Japan)
Material： Biochimie
Volume： 174  Page： 49-56  Publication year： 2020 
JST Material Number： B0147A  ISSN： 0300-9084  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Eukaryotic gene expression can...

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Thesaurus term： *interaction ,  mRNA ,  regulatory gene ,  *Proteins ,  Mammalia ,  complex (substance) ,  function analysis ,  Eukaryota ,  Pharmacology ,  gene expression ,  in vitro experiment ,  *binding protein ,  controlling element ,  translational repression ,  translational control ,  Vertebrata ,  organism ,  molecular genetic phenomenon

Author keywords (5)： ZFP36L1 ,  AU-Rich element ,  CCR4-NOT ,  Deadenylation ,  Translation

JST classification (1)： Gene expression  (EC02040Q)

Terms in the title (5)： ARE ,  脱アデニル化 ,  非依存性 ,  翻訳 ,  相互作用