Art

J-GLOBAL ID：202002262676969309   Reference number：20A0277184

Oxidative misfolding of Cu/Zn-superoxide dismutase triggered by non-canonical intramolecular disulfide formation

非カノニカル分子内ジスルフィド形成により誘発されたCu/Znスーパーオキシドジスムターゼの酸化的誤折畳み【JST・京大機械翻訳】

Author (7)： Anzai Itsuki (Department of Chemistry, Keio University, Yokohama, 223-8522, Japan) ,  Tokuda Eiichi (Department of Chemistry, Keio University, Yokohama, 223-8522, Japan) ,  Handa Sumika (Department of Chemistry, Keio University, Yokohama, 223-8522, Japan) ,  Misawa Hidemi (Division of Pharmacology, Faculty of Pharmacy, Keio University, Tokyo, 105-8512, Japan) ,  Akiyama Shuji (Research Center of Integrative Molecular Systems (CIMoS), Institute for Molecular Science, National Institutes of Natural Sciences, Okazaki, 444-8585, Japan) ,  Akiyama Shuji (Department of Functional Molecular Science, SOKENDAI (The Graduate University for Advanced Studies), Okazaki, 444-8585, Japan) ,  Furukawa Yoshiaki (Department of Chemistry, Keio University, Yokohama, 223-8522, Japan)
Material： Free Radical Biology & Medicine  (Free Radical Biology and Medicine)
Volume： 147  Page： 187-199  Publication year： 2020 
JST Material Number： D0414C  ISSN： 0891-5849  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Misfolded Cu/Zn-superoxide dis...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A0277184&from=J-GLOBAL&jstjournalNo=D0414C") }}

Thesaurus term： metal ion ,  subset ,  oxidative stress ,  steric conformation ,  mercapto group ,  spinal cord ,  amyotrophic lateral sclerosis ,  aggregate ,  hydrogen peroxide ,  cytotoxicity ,  *oxidation ,  *disulfide ,  *folding(morphology) ,  disulfide bond ,  oxidation environment

Author keywords (3)： Protein misfolding ,  Disulfide formation ,  Neurodegenerative diseases

JST classification (2)： Cell physiology in general  (EF02010S) ,  Enzyme in general  (EB09010D)

Terms in the title (7)： ジスルフィド ,  誘発 ,  Cu ,  Zn ,  スーパーオキシドジスムターゼ ,  酸化 ,  折畳み