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J-GLOBAL ID:202002268506253110   Reference number:20A0872042

Long-term Effects of the Janus Kinase 1/2 Inhibitor Ruxolitinib on Pulmonary Hypertension and the Cardiac Function in a Patient with Myelofibrosis

骨髄線維症患者における肺高血圧症と心機能に対するJanusキナーゼ1/2阻害剤ルキソリチニブの長期効果
Author (11):
Material:
Volume: 59  Issue:Page: 229-233(J-STAGE)  Publication year: 2020 
JST Material Number: U0033A  ISSN: 1349-7235  Document type: Article
Article type: 原著論文  Country of issue: Japan (JPN)  Language: ENGLISH (EN)
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Drug therapy(=pharmacotherapy)for hematologic diseases in general  ,  Cardiovascular system diseases 
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Reference (15):
  • 1. Tefferi A. Myeloproliferative neoplasms: a decade of discoveries and treatment advances. Am J Hematol 91: 50-58, 2016.
  • 2. Tefferi A. Primary myelofibrosis: 2017 update on diagnosis, risk-stratification, and management. Am J Hematol 91: 1262-1271, 2016.
  • 3. Harrison C, Kiladjian JJ, Al-Ali HK, et al. JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med 366: 787-798, 2012.
  • 4. Tabarroki A, Lindner DJ, Visconte V, et al. Ruxolitinib leads to improvement of pulmonary hypertension in patients with myelofibrosis. Leukemia 28: 1486-1493, 2014.
  • 5. Yamauchi-Takihara K, Kishimoto T. A novel role for STAT3 in cardiac remodeling. Trends Cardiovasc Med 10: 298-303, 2000.
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