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J-GLOBAL ID：202002268702896699   Reference number：20A0877739

Attenuation of experimental autoimmune uveoretinitis in mice by IKKβ inhibitor IMD-0354

IKKβ阻害剤IMD-0354によるマウスにおける実験的自己免疫ぶどう膜網膜炎の減弱【JST・京大機械翻訳】

Author (14)： Liu Ye (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Liu Ye (Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China) ,  Kitaichi Nobuyoshi (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Kitaichi Nobuyoshi (Department of Ophthalmology, Health Sciences University of Hokkaido, Sapporo, Japan) ,  Wu Di (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Hase Keitaro (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Satoh Masashi (Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan) ,  Iwata Daiju (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Namba Kenichi (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Kanda Atsuhiro (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Noda Kousuke (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan) ,  Itai Akiko (Institute of Medical Molecular Design Inc, Tokyo, Japan) ,  Iwabuchi Kazuya (Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan) ,  Ishida Susumu (Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 525  Issue： 3  Page： 589-594  Publication year： 2020 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Uveitis is a sight-threatening...

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Thesaurus term： Inflammation ,  edema ,  human ,  NF-kappaB ,  Uveitis ,  *Retina ,  Th1 cell ,  eye disease ,  *Autoimmunity ,  *Retinitis ,  inflammatory cytokine ,  in vitro experiment ,  *grape ,  Th17 Cells ,  Signal Transduction
Semi thesaurus term： cellular signal transduction , 【Automatic Indexing@JST】

Author keywords (4)： EAU ,  Uveitis ,  IKKβ ,  NF-κB

JST classification (2)： Cell physiology in general  (EF02010S) ,  Function of cell components  (EF03060C)

Terms in the title (9)： IKKβ ,  阻害剤 ,  IMD-0354 ,  マウス ,  実験 ,  自己免疫 ,  ぶどう膜 ,  網膜炎 ,  減弱