Art

J-GLOBAL ID：202002273495821085   Reference number：20A1410071

Antioxidant nanomedicine with cytoplasmic distribution in neuronal cells shows superior neurovascular protection properties

神経細胞における細胞質分布を伴う抗酸化ナノ医療は優れた神経血管保護特性を示す【JST・京大機械翻訳】

Author (21)： Mujagic Arnela (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Mujagic Arnela (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Marushima Aiki (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Marushima Aiki (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Nagasaki Yukio (Graduate School of Pure and Applied Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Hosoo Hisayuki (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Hosoo Hisayuki (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Hirayama Aki (Center for Integrative Medicine, Tsukuba University of Technology, Kasuga 4-12-7, Tsukuba, Ibaraki, Japan) ,  Puentes Sandra (Graduate School of Systems and Information Engineering, University of Tsukuba, Tennodai 1-1-1, Ibaraki, Japan) ,  Takahashi Toshihide (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Takahashi Toshihide (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Tsurushima Hideo (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Tsurushima Hideo (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Suzuki Kensuke (Department of Neurosurgery, Saitama Medical Center, Dokkyo Medical University, Minami-Koshigaya 2-1-50, Koshigaya, Saitama, Japan) ,  Matsui Hirofumi (Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Ishikawa Eiichi (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Ishikawa Eiichi (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Matsumaru Yuji (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Matsumaru Yuji (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Matsumura Akira (Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan) ,  Matsumura Akira (Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan)
Material： Brain Research  (Brain Res)
Volume： 1743  Page： Null  Publication year： 2020 
JST Material Number： A0705B  ISSN： 0006-8993  CODEN： BRREA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： This study investigated whethe...

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Thesaurus term： polarization(phenomenon) ,  *neuron ,  blood-brain barrier ,  *cytoplasm ,  artery ,  capture ,  survival ratio ,  cerebral ischemia ,  reperfusion ,  active oxygen ,  astrocyte ,  nano particle ,  microglia ,  nitrogen heterocyclic compound ,  aromatic compound ,  vic-polynitrogen compound
Semi thesaurus term： 抗酸化剤 , 【Automatic Indexing@JST】

Author keywords (3)： Neuroprotection ,  RNPs ,  Reactive oxygen species

JST classification (4)： Basic research of other drugs acting on central nervous system  (GW03120U) ,  Central nervous system  (EJ12030F) ,  Basic neurology  (GN01020W) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (1)： Edaravone

Terms in the title (8)： 神経細胞 ,  細胞質 ,  分布 ,  酸化 ,  ナノ医療 ,  神経 ,  血管 ,  保護特性