Art

J-GLOBAL ID：202002273786291606   Reference number：20A0636033

Efficacy of an anti-cancer strategy targeting SET in canine osteosarcoma

イヌ骨肉腫のSETを標的とする抗腫瘍戦略の有効性

Author (4)： TSUJI Shunya (Laboratory of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan) ,  OHAMA Takashi (Laboratory of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan) ,  NAKAGAWA Takayuki (The Laboratory of Veterinary Surgery and the Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan) ,  SATO Koichi (Laboratory of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan)
Material： Journal of Veterinary Medical Science (Web)
Volume： 81  Issue： 10  Page： 1424-1430(J-STAGE)  Publication year： 2019 
JST Material Number： U1094A  ISSN： 1347-7439  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *oncoprotein ,...
Semi thesaurus term： E2F-1 ,...

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Author keywords (4)： canine ,  osteosarcoma ,  protein phosphatase 2A (PP2A) ,  SET

JST classification (2)： Medical pharmaceuticals for animals  (FE01050B) ,  Other animal diseases  (FE02060T)

Substance index (1)： Fingolimod

Reference (27)：

• 1. Alvarez, F. J., Kisseberth, W., Hosoya, K., Lara-Garcia, A., Kosarek, C., Murahari, S., Au, J. L. S., Wientjes, M. G., Couto, J. and Couto, G. 2014. Postoperative adjuvant combination therapy with doxorubicin and noncytotoxic suramin in dogs with appendicular osteosarcoma. J. Am. Anim. Hosp. Assoc. 50: 12-18.
• 2. Barroga, E. F., Kadosawa, T., Okumura, M. and Fujinaga, T. 1999. Establishment and characterization of the growth and pulmonary metastasis of a highly lung metastasizing cell line from canine osteosarcoma in nude mice. J. Vet. Med. Sci. 61: 361-367.
• 3. Brander, D. M., Friedman, D. R., Volkheimer, A. D., Christensen, D. J., Rassenti, L. Z., Kipps, T. J., Guadalupe, E., Chen, Y., Zhang, D., Wang, X., Davis, C., Owzar, K. and Weinberg, J. B. 2019. SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia. Br. J. Haematol. 184: 605-615.
• 4. Chandhanayingyong, C., Kim, Y., Staples, J. R., Hahn, C. and Lee, F. Y. 2012. MAPK/ERK Signaling in Osteosarcomas, Ewing Sarcomas and Chondrosarcomas: Therapeutic Implications and Future Directions. Sarcoma 2012: 404810.
• 5. Chen, W., Possemato, R., Campbell, K. T., Plattner, C. A., Pallas, D. C. and Hahn, W. C. 2004. Identification of specific PP2A complexes involved in human cell transformation. Cancer Cell 5: 127-136.

Terms in the title (7)： イヌ ,  骨肉腫 ,  SET ,  標的 ,  腫瘍 ,  戦略 ,  有効性