Art

J-GLOBAL ID：202002282785158869   Reference number：20A0635859

The clarified role of interleukin-19 in the inflammatory bowel disease and hypersensitivity: Insights from animal models and humans

炎症性腸疾患と過敏症におけるインターロイキン19の明確な役割 動物モデルとヒトからの洞察

Author (3)： FUJIMOTO Yasuyuki (Laboratory of Veterinary Pharmacology, Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Sciences, Izumisano, Osaka 598-8531, Japan) ,  AONO Kimiya (Laboratory of Veterinary Pharmacology, Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Sciences, Izumisano, Osaka 598-8531, Japan) ,  AZUMA Yasu-Taka (Laboratory of Veterinary Pharmacology, Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Sciences, Izumisano, Osaka 598-8531, Japan)
Material： Journal of Veterinary Medical Science (Web)
Volume： 81  Issue： 8  Page： 1067-1073(J-STAGE)  Publication year： 2019 
JST Material Number： U1094A  ISSN： 1347-7439  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Inflammation ,...
Semi thesaurus term： immunological reaction ,...

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Author keywords (4)： anti-inflammation ,  hypersensitivity ,  inflammatory bowel disease ,  interleukin-19

JST classification (2)： Immunological reaction in general  (ED03010T) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Reference (39)：

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• 3. Azuma, Y. T., Matsuo, Y., Nakajima, H., Yancopoulos, G. D., Valenzuela, D. M., Murphy, A. J., Karow, M. and Takeuchi, T. 2011. Interleukin-19 is a negative regulator of innate immunity and critical for colonic protection. J. Pharmacol. Sci. 115: 105-111.
• 4. Azuma, Y. T., Nakajima, H. and Takeuchi, T. 2011. IL-19 as a potential therapeutic in autoimmune and inflammatory diseases. Curr. Pharm. Des. 17: 3776-3780.
• 5. Bian, R., Tang, J., Hu, L., Huang, X., Liu, M., Cao, W. and Zhang, H. 2018. (E)-phenethyl 3-(3,5-dihydroxy-4-isopropylphenyl) acrylate gel improves DNFB-induced allergic contact hypersensitivity via regulating the balance of Th1/Th2/Th17/Treg cell subsets. Int. Immunopharmacol. 65: 8-15.

Terms in the title (8)： 炎症性腸疾患 ,  過敏症 ,  インターロイキン19 ,  役割 ,  動物 ,  モデル ,  ヒト ,  洞察