Art

J-GLOBAL ID：202002285990942192   Reference number：20A2458158

Ester derivatives of phyllohydroquinone effectively deliver the active form of vitamin K₁ topically, owing to their non-photosensitivity

フィロヒドロキノンのエステル誘導体は,非光感受性に局所的にビタミンK_1の活性型を有効に送達する【JST・京大機械翻訳】

Author (11)： Goto Shotaro (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Setoguchi Shuichi (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Nagata-Akaho Nami (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Terada Kazuki (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Watase Daisuke (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Yamakawa Hirofumi (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Toki Erina (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Koga Mitsuhisa (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Matsunaga Kazuhisa (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Karube Yoshiharu (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Takata Jiro (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan)
Material： European Journal of Pharmaceutical Sciences  (Eur J Pharm Sci)
Volume： 155  Page： Null  Publication year： 2020 
JST Material Number： W0673A  ISSN： 0928-0987  CODEN： EPSCED  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Topical application of phylloq...

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Thesaurus term： *ester ,  *Vitamin K ,  human ,  Sunlight ,  photolysis/photodisintegration ,  local administration ,  prodrug ,  keratinocyte ,  phototoxicity ,  singlet oxygen ,  ultraviolet-A ,  cell survival rate ,  *photosensitivity ,  HaCaT Cells
Semi thesaurus term： 光安定性 , 【Automatic Indexing@JST】

Author keywords (5)： Photostability ,  Phototoxicity ,  Phylloquinone ,  Skin application ,  Vitamin K

JST classification (1)： Basic dermatology  (GF01020Y)

Terms in the title (4)： エステル誘導体 ,  光感受性 ,  活性 ,  送達