Art

J-GLOBAL ID：202002286023496940   Reference number：20A1441611

Brain pharmacokinetics and biodistribution of ¹¹C-labeled isoproterenol in rodents

齧歯類における13C標識イソプロテレノールの脳薬物動態と生体内分布【JST・京大機械翻訳】

Author (13)： Ogata Aya (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Ogata Aya (Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science, Kani, Japan) ,  Kimura Yasuyuki (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Ikenuma Hiroshi (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Ikenuma Hiroshi (Field of Biological Molecular Sciences, United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan) ,  Yamada Takashi (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Abe Junichiro (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Koyama Hiroko (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Koyama Hiroko (Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan) ,  Suzuki Masaaki (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Ichise Masanori (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Kato Takashi (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Ito Kengo (Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan)
Material： Nuclear Medicine and Biology  (Nucl Med Biol)
Volume： 86-87  Page： 52-58  Publication year： 2020 
JST Material Number： D0652A  ISSN： 0969-8051  CODEN： NMBIEO  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Isoproterenol is a non-selecti...

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Thesaurus term： plasma(blood) ,  plasma concentration ,  receptor ,  heartbeat ,  *biodistribution ,  metabolite ,  human(primates) ,  rat ,  pharmacology ,  high performance liquid chromatography ,  Alzheimer disease ,  PET(tomography) ,  catecholamine ,  aminoalcohol ,  secondary amine ,  secondary alcohol
Semi thesaurus term： ホモジネート ,  アゴニスト , 【Automatic Indexing@JST】

Author keywords (5)： Isoproterenol ,  Positron emission tomography ,  Brain pharmacokinetics ,  Radio-HPLC ,  Radiometabolites

JST classification (5)： Basic research of anti-inflammatory drugs  (GW15010T) ,  Receptors on cell membrane  (EF04030C) ,  Research methods  (GV01020U) ,  Basic research of drugs acting on respiration and respiratory system  (GW08010J) ,  Basic neurology  (GN01020W)

Substance index (1)： Isoproterenol

Terms in the title (6)： 齧歯類 ,  標識 ,  イソプロテレノール ,  脳 ,  薬物動態 ,  生体内分布