Art

J-GLOBAL ID：202002286684150214   Reference number：20A2056877

ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome

ASCは血小板活性化を制御し,NLRP3インフラマソームとは無関係に血栓形成に寄与する【JST・京大機械翻訳】

Author (11)： Watanabe Sachiko (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan) ,  Usui-Kawanishi Fumitake (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan) ,  Usui-Kawanishi Fumitake (Department of Pharmaceutical Engineering, Toyama Prefectural University, Toyama, Japan) ,  Komada Takanori (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan) ,  Karasawa Tadayoshi (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan) ,  Kamata Ryo (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan) ,  Yamada Naoya (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan) ,  Kimura Hiroaki (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan) ,  Dezaki Katsuya (Department of Physiology, Jichi Medical University, Tochigi, Japan) ,  Ohmori Tsukasa (Department of Biochemistry, Jichi Medical University, Tochigi, Japan) ,  Takahashi Masafumi (Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 531  Issue： 2  Page： 125-132  Publication year： 2020 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Platelets are critical mediato...

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Thesaurus term： peptide ,  Inflammation ,  *thrombocyte ,  *Thrombosis ,  Collagen ,  Thrombin ,  phosphorylation ,  homeostasis ,  Cytosol ,  interleukin 1 ,  Interleukin-1beta ,  Erk1/2 ,  *Inflammasomes ,  Signal Transduction ,  *Thromboembolism ,  Scleroproteins ,  animal protein
Semi thesaurus term： cellular signal transduction ,  アゴニスト , 【Automatic Indexing@JST】

Author keywords (4)： Cerebral infarction ,  Deep vein thrombosis ,  Interleukin ,  Mice

JST classification (2)： Function of cell components  (EF03060C) ,  Fibrinolysis and blood coagulation  (EJ03040S)

Terms in the title (4)： ASC ,  血小板活性化 ,  NLRP3インフラマソーム ,  血栓形成