Art

J-GLOBAL ID：202002290069779437   Reference number：20A1172609

Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon⁺ α-cells

すい島-自律的インスリンおよび平滑化仲介シグナル伝達はグルカゴン+α-細胞の同一性変化を調節する【JST・京大機械翻訳】

Author (20)： Cigliola Valentina (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  Cigliola Valentina (Department of Cell Biology, Duke University Medical Center, Durham, NC, USA) ,  Ghila Luiza (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  Ghila Luiza (Department of Clinical Science and KG Jebsen Center for Diabetes Research, University of Bergen, Bergen, Norway) ,  Thorel Fabrizio (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  van Gurp Leon (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  Baronnier Delphine (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  Oropeza Daniel (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  Gupta Simone (Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN, USA) ,  Miyatsuka Takeshi (Department of Metabolism and Endocrinology, Graduate School of Medicine , Juntendo University , Tokyo, Japan) ,  Kaneto Hideaki (Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan) ,  Magnuson Mark A. (Departments of Molecular Physiology and Biophysics, Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA) ,  Osipovich Anna B. (Departments of Molecular Physiology and Biophysics, Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA) ,  Sander Maike (Department of Pediatrics and Cellular and Molecular Medicine, University of California, San Diego, CA, USA) ,  Wright Christopher E. V. (Department of Cell and Developmental Biology, Program in Developmental Biology and Center for Stem Cell Biology, Vanderbilt University School of Medicine, Nashville, TN, USA) ,  Thomas Melissa K. (Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN, USA) ,  Furuyama Kenichiro (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  Chera Simona (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland) ,  Chera Simona (Department of Clinical Science and KG Jebsen Center for Diabetes Research, University of Bergen, Bergen, Norway) ,  Herrera Pedro L. (Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabete, Faculty of Medicine, University of Geneva, Geneva, Switzerland)
Material： Nature Cell Biology  (Nat Cell Biol)
Volume： 20  Issue： 11  Page： 1267-1277  Publication year： 2018 
JST Material Number： W1369A  ISSN： 1465-7392  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: The mechanisms that ...

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Thesaurus term： *insulin ,  *Glucagon ,  Vertebrata ,  adaptability ,  *smoothing ,  inactivation ,  characterization ,  *Islets of Langerhans ,  cell fate ,  Insulin-Secreting Cells ,  Smoothened protein ,  Cell Plasticity ,  *Signal Transduction ,  *hypoglycemic drug ,  *metabolic drug ,  *carbohydrate metabolic drug ,  *drug ,  animal
Semi thesaurus term： *cellular signal transduction , 【Automatic Indexing@JST】

JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Terms in the title (8)： すい島 ,  インスリン ,  平滑化 ,  仲介 ,  シグナル伝達 ,  グルカゴン ,  細胞 ,  調節