Art

J-GLOBAL ID：202002290801535339   Reference number：20A0498621

T Cell Dysfunction and Exhaustion in Cancer

癌におけるT細胞機能障害と消耗【JST・京大機械翻訳】

Author (9)： Zhang Zhen (Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China) ,  Liu Shasha (Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China) ,  Zhang Bin (Department of Hematology/Oncology, School of Medicine, Northwestern University, Chicago, IL, United States) ,  Qiao Liang (Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, IL, United States) ,  Zhang Yi (Fels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States) ,  Zhang Yi (Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China) ,  Zhang Yi (Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China) ,  Zhang Yi (Henan Key Laboratory for Tumor Immunology and Biotherapy, Zhengzhou, China) ,  Zhang Yi (School of Life Sciences, Zhengzhou University, Zhengzhou, China)
Material： Frontiers in Cell and Developmental Biology (Web)
Volume： 8  Page： 17  Publication year： 2020 
JST Material Number： U7062A  ISSN： 2296-634X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Tumor immunotherapy is a promi...

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Thesaurus term： dysfunction ,  antigen ,  therapeutic planning ,  receptor ,  tumorigenesis ,  tumor ,  advanced cancer ,  effector ,  *T cell ,  immunotherapy
Semi thesaurus term： 癌患者 ,  分子機構 ,  メモリーT細胞 ,  癌免疫療法 , 【Automatic Indexing@JST】

Author keywords (5)： T cells dysfunction ,  intrinsic factors ,  extrinsic factors ,  tumor microenvironment ,  cancer immunotherapy

JST classification (2)： Gene expression  (EC02040Q) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (118)：

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• Alfei F., Kanev K., Hofmann M., Wu M., Ghoneim H. E., Roelli P., et al (2019). TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature 571 265-269. doi: 10.1038/s41586-019-1326-9
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• Benner B., Scarberry L., Suarez-Kelly L. P., Duggan M. C., Campbell A. R., Smith E., et al (2019). Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro. J. Immunother. Cancer 7:140. doi: 10.1186/s40425-019-0622-0

Terms in the title (4)： 癌 ,  T細胞 ,  機能障害 ,  消耗