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J-GLOBAL ID：202002296957739963   Reference number：20A2301030

Screening siRNAs against host glycosylation pathways to develop novel antiviral agents against hepatitis B virus

B型肝炎ウイルスに対する新規抗ウイルス薬開発のための宿主グリコシル化経路に対するsiRNAのスクリーニング

Author (14)： Ito Kiyoaki (Department of Gastroenterology, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Angata Kiyohiko (Glycoscience and Glycotechnology Research Group, Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan) ,  Kuno Atsushi (Glycoscience and Glycotechnology Research Group, Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan) ,  Okumura Akinori (Department of Gastroenterology, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Sakamoto Kazumasa (Department of Gastroenterology, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Inoue Rieko (Department of Gastroenterology, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Morita Naoko (Department of Gastroenterology, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Watashi Koichi (Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan) ,  Wakita Takaji (Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan) ,  Tanaka Yasuhito (Department of Virology & Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan) ,  Sugiyama Masaya (The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan) ,  Mizokami Masashi (The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan) ,  Yoneda Masashi (Department of Gastroenterology, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Narimatsu Hisashi (Glycoscience and Glycotechnology Research Group, Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan)
Material： Hepatology Research  (Hepatol Res)
Volume： 50  Issue： 10  Page： 1128-1140  Publication year： Oct. 2020 
JST Material Number： W1284A  ISSN： 1386-6346  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *Hepatitis B virus ,...
Semi thesaurus term： GALNT7 ,...

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Author keywords (5)： GALNT7 ,  glycosylation ,  HBsAg ,  HBV DNA ,  ST8SIA3

JST classification (2)： Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Virus physiology in general  (EG04041H)

Terms in the title (8)： B型肝炎ウイルス ,  抗ウイルス薬 ,  開発 ,  宿主 ,  グリコシル化 ,  経路 ,  siRNA ,  スクリーニング