Art

J-GLOBAL ID：202102229919721462   Reference number：21A0059517

The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia

機能性消化不良の治療薬を評価するための,わさびの辛味成分であるアリルイソチオシアネートにより誘発される胃運動性障害のげっ歯類モデル

Author (7)： Hashimoto Kazuki (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai International University, 1 Gumyo, Togane, Chiba, 283-8555, Japan) ,  Tashima Kimihito (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai International University, 1 Gumyo, Togane, Chiba, 283-8555, Japan) ,  Tashima Kimihito (Center of Pharmacological Kampo Research, Josai International University, 1 Gumyo, Togane, Chiba, 283-8555, Japan) ,  Imai Taku (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai International University, 1 Gumyo, Togane, Chiba, 283-8555, Japan) ,  Matsumoto Kenjiro (Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, 607-8414, Japan) ,  Horie Syunji (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai International University, 1 Gumyo, Togane, Chiba, 283-8555, Japan) ,  Horie Syunji (Center of Pharmacological Kampo Research, Josai International University, 1 Gumyo, Togane, Chiba, 283-8555, Japan)
Material： Journal of Pharmacological Sciences (Web)  (J Pharmacol Sci (Web))
Volume： 145  Issue： 1  Page： 122-129  Publication year： 2021 
JST Material Number： U0667A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： 13C breath test ,...

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Author keywords (5)： Mice ,  Allyl isothiocyanate ,  Gastric motility ,  ¹³C-acetic acid breath test ,  Daikenchuto

JST classification (4)： Basic medicine on digestive system  (GH01020E) ,  Research methods  (GV01020U) ,  Basic research of drugs acting on digestive system  (GW09010Q) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (5)： Acotiamide ,  Allyl isothiocyanate ,  Itopride ,  Neostigmine ,  Mosapride

Terms in the title (11)： 機能性消化不良 ,  治療薬 ,  評価 ,  わさび ,  辛味成分 ,  アリルイソチオシアネート ,  誘発 ,  胃 ,  運動性障害 ,  げっ歯類 ,  モデル