Precision Medicine using microRNA in Treatment of Colorectal Cancer

YOKOYAMA YUKI; MORIMOTO YOSHIHIRO; HATA TSUYOSHI; INOUE AKIRA; INOUE AKIRA; OTSUKA MASAHISA; OTSUKA MASAHISA; HIRAKI MASAYUKI; HIRAKI MASAYUKI; XIN Wu; YAMAMOTO HIROFUMI; YAMAMOTO HIROFUMI

Art

J-GLOBAL ID：202102234686905619 Reference number：21A0359271

Precision Medicine using microRNA in Treatment of Colorectal Cancer

大腸癌診療におけるprecision medicine 核酸医薬を用いた大腸癌のprecision medicine

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Author (12)： , , , , , , , , , , ,
Material：
Volume： 65 Issue： 4 Page： 335-343 Publication year： Jan. 29, 2021
JST Material Number： Z0928A ISSN： 0021-4949 Document type： Article
Article type：解説 Country of issue： Japan (JPN) Language： JAPANESE (JA)

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Tumors(=neoplasms)of digestive system , Basic oncology in general , Basic research of antitumor(=antineoplastic)drugs

Reference (8)：

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Inoue A, Mizushima T, Wu X, et al : A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-κB Signaling in KRAS-Mutant Colon Cancer Cells. Mol Cancer Ther 17 : 977-987, 2018
Nakaya T, Ogawa S, Manabe I, et al : KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells. Cancer Res 74 : 2882-2891, 2014
Morimoto Y, Mizushima T, Wu X, et al : miR-4711-5p Regulates Cancer Stemness and Cell Cycle Progression via KLF5, MDM2 and TFDP1 in Colon Cancer Cells. Br J Cancer 122 : 1037-1049, 2020
Beg MS, Brenner AJ, Sachdev J, et al : Phase I Study of MRX34, a Liposomal miR-34a Mimic, Administered Twice Weekly in Patients With Advanced Solid Tumors. Phase I Study of MRX34, a Liposomal miR-34a Mimic, Administered Twice Weekly in Patients With Advanced Solid Tumors. Invest New Drugs 35 : 180-188, 2017

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