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J-GLOBAL ID：202102238177977118   Reference number：21A0460565

Transmembrane phospholipid translocation mediated by Atg9 is involved in autophagosome formation

Atg9により仲介される膜貫通リン脂質転座はオートファゴソーム形成に関与する【JST・京大機械翻訳】

Author (4)： Orii Minami (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Tsuji Takuma (Laboratory of Molecular Cell Biology, Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Ogasawara Yuta (Laboratory of Molecular Cell Biology, Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Fujimoto Toyoshi (Laboratory of Molecular Cell Biology, Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan)
Material： Journal of Cell Biology  (JCB)
Volume： 220  Issue： 3  Page： Null  Publication year： 2021 
JST Material Number： C0575A  ISSN： 0021-9525  CODEN： JCLBA3  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The mechanism of isolation mem...

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Thesaurus term： symmetry ,  electron microscope ,  biosynthesis ,  bilayer ,  Yeasts ,  freezing ,  lecithin ,  *phospholipid ,  phosphatidylserine ,  liposome ,  *translocation (genetics) ,  Autophagy ,  *Autophagosomes ,  lipid transfer ,  microorganism ,  thin film ,  lipid membrane ,  layer ,  multilayer (molecule) ,  multilayer ,  lipid bilayer membrane ,  *cellular genetic phenomenon
Semi thesaurus term： 機能性 , 【Automatic Indexing@JST】

JST classification (2)： Cell physiology in general  (EF02010S) ,  Cell components in general  (EF03010Z)

Reference (42)：

• Bento. Mammalian autophagy: How does it work?. Annu. Rev. Biochem. 2016, 85, 685. doi:10.1146/annurev-biochem-060815-014556
• Brombacher. Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. J. Biol. Chem. 2009, 284, 4846. doi:10.1074/jbc.M807505200
• Cheng. Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries. Nat. Commun. 2014, 5, 3207. doi:10.1038/ncomms4207
• Chowdhury. Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex. Proc. Natl. Acad. Sci. USA. 2018, 115, E9792. doi:10.1073/pnas.1811874115
• Dall’Armi. The role of lipids in the control of autophagy. Curr. Biol. 2013, 23, R33. doi:10.1016/j.cub.2012.10.041

Terms in the title (5)： ATG9 ,  仲介 ,  リン脂質 ,  転座 ,  オートファゴソーム